学院简介     深圳大学高等研究院是深圳大学新成立的一个包含本科与研究生培养、侧重交叉学科教学和研究的校内新型教育机构。高等研究院是深圳大学内部一个探索全面改革创新、实行特殊管理体制的、开展交叉学科创新人才培养和科学研究的学术特区,实行教授治院。高等研究院将与香港和海外著名高校合作,借鉴国际一流研究型大学通行的管理与运行机制,引进具有一流视野的资深······
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高等研究院系列学术讲座之六十四

作者:admin | 发布时间:2017-04-07 | 浏览次数:381
下一篇文章:高等研究院系列学术讲座之六十五

Brain Fatty Acid Metabolism Mediates Leptin’s Central Effect of Reducing Body Weight

Dr. Su GAO

Project Scientist, Cedars-Sinai Medical Center, Los Angeles, California United States


About the Speaker

Dr. Gao graduated from Peking University Health Sciences Center (former Beijing Medical University) with a medical degree. He conducted his Ph.D. thesis research at the world-renowned Johns Hopkins School of Medicine in the United States. Currently he is a Project Scientist at Cedars-Sinai Medical Center at Los Angeles, California.


Talk Information

In this seminar, I will talk about the role of fatty acid metabolism in the central nervous system underlying the regulation of energy balance. Brain fatty acid metabolism has recently been shown to mediate aspect of the central control of feeding behavior and body weight homeostasis. In this regard, malonyl-CoA, an intermediate in fatty acid biosynthetic pathway, has emerged as a key player. I will focus on the action of malonyl-CoA in the hypothalamus, a critical brain site in mediating the control of appetite and energy homeostasis. In particular, I will delineate the role of malonyl-CoA in the hypothalamus in mediating the intracellular signaling pathways underlying leptin’s effect of suppressing appetite and reducing body weight. I will further present data highlighting the potential downstream targets of malonyl-CoA in leptin’s hypothalamic intracellular signaling pathway. Finally, I will discuss future directions aimed at further understanding malonyl-CoA signaling mechanisms in the hypothalamus.

时间:2017年4月10号上午9:30-10:30

地点:办公楼628会议室(原620-12会议室)

All are welcome!