Ph.D, Research Scientist
Address: Room 358,Administration Building,Shenzhen University,3688 Avenue Nanhai, Nanshan District,Shenzhen, Guangdong, China, 518060
Osnabrück University, and Center for Nanotechnology (CeNTech) of Münster University, Germany.
Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences
School of medicine, Yale University
2004-2006 Research Assistant
Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences
Chemical modification and functionalization of DNA nucleobases
DNA fluorescence label
“Click” reaction induced cross-linked DNA
Fabrication of DNA self-assembled nanostructures
Recombinant non-natural amino acids and biosynthetic protein
protein post-translational modification: lysine acetylation or methylation; phosphorylation of serine, threonine, tyrosine analogues
H. Xiong, N. Reynolds, C. Fan, M. Englert, D. Hoyer, S. Miller and D. Söll*, Dual Genetic Encoding of Acetyl-lysine and Non-deacetylatable Thioacetyl-lysine Mediated by Flexizyme. Angew. Chem. Int. Ed. 2016, 55, 4083-4086.
C. Fan*, H. Xiong, N. Reynolds and D. Söll*, Rationally evolving tRNAPyl for efficient incorporation of noncanonical amino acids. Nucleic Acid Research. 2015, 43(22): e156
H. Xiong and F. Seela*, Cross-Linked DNA: Site Selective “Click” Ligation in Duplexes with Bis-Azides and Stability Changes Caused by Internal Cross-Links. Bioconjugate Chem., 2012, 23, 1230-1243.
H. Xiong, P. Leonard and F. Seela*, Construction and Assembly of Branched Y-shaped DNA: “Click” Chemistry Performed on Dendronized 8-Aza-7-deazaguanine Oligonucleotides. Bioconjugate Chem., 2012, 23, 856-870.
H. Xiong and F. Seela*, Stepwise “Click” Chemistry for the Template Independent Construction of a Broad Variety of Cross-linked Oligonucleotides: Influence of Linker Length, Position and Linking Number on DNA Duplex Stability. J. Org. Chem., 2011, 76, 5584-5597.
G. Qing, H. Xiong (Co-first authors), F. Seela*a and T. Sun*b, Spatially Controlled DNA Nano-patterns by “Click” Chemistry Using Oligonucleotides with Different Anchoring Sites. J. Am. Chem. Soc., 2010, 132, 15228-15232.
F. Seela*, H. Xiong and S. Budow, Synthesis and “Double Click” Density Functionalization of 8-Aza-7-deazaguanine DNA Bearing Branched Side Chains with Terminal Triple Bonds. Tetrahedron, 2010, 66, 3930-3943.
F. Seela*, H. Xiong, P. Leonard and S. Budow, 8-Aza-7-deazaguanine Nucleosides and Oligonucleotides with Octadiynyl Side Chains: Synthesis, Functionalization by the Azide-Alkyne ‘Click’ Reaction and Nucleobase Specific Fluorescence Quenching of Coumarin Dye Conjugates. Org. Biomol. Chem., 2009, 7, 1374-1387.
Q. Yang, S. Ma*, J. Li, F. Xiao* and H. Xiong, A water-compatible, highly active and reusable PEG-coated mesoporous silica-supported palladium complex and its application in Suzuki coupling reactions. Chem. Commun., 2006, 2495-2497.
H. Xiong, F. Shi, J. Peng and Y. Deng*, Synthesis of supported gold catalysts for selective oxidation of cyclohexane with air. Chin. J. Mol. Catal., 2005, 19(3), 204-207.
H. Xiong, F. Shi and Y. Deng*, Synthesis and application of supported cobalt catalyst for selective oxidation of cyclohexane and toluene. Chin. J. Catal., 2004, 25(11), 887-891.
F. Shi, H. Xiong, Y. Gu, S. Guo and Y. Deng*, The first non-acid catalytic synthesis of tert-butyl ether from tert-butyl alcohol using ionic liquid as dehydrator. Chem. Commun., 2003, 1054-1055.