
博士, 研究员
邮箱:hai.xiong@szu.edu.cn
地址:深圳市南山区南海大道3688号
深圳大学办公楼352室,518060
教育背景:
2006-2012年:德国奥斯纳布吕克大学(Osnabrück)和明斯特大学(Münster)纳米技术中心 理学博士
2001-2004年:中科院兰州化学物理研究所 理学硕士
1997-2001年:南昌大学 理学学士
工作经历:
2012-2016年:耶鲁大学 博士后
2004-2006年:中科院上海有机化学研究所 研究助理
研究方向:
非天然核酸的化学修饰和功能团化
DNA生物传感 / 细胞影像
DNA纳米自组装及其药物控释
DNA/polymer荧光水凝胶的制备及应用
超分子发光材料
定位装载非天然氨基酸和修饰蛋白的功能团化
所获奖励:
2018年:广东省珠江人才计划-青年拔尖人才
2017年:深圳市南山区领航人才
2016年:深圳市海外高层次人才(孔雀计划)
学术兼职:
Chinese Chemical Letters: 青年编委
Frontiers in Bioengineering and Biotechnology: 首席客座编辑-Lead Guest Editor
科研项目:
1). 深圳市海外高层次人才 “孔雀计划” 项目,2017/11-2020/12,结题,主持;
2). 深圳市基础研究自由探索项目,2018/04-2020/03,结题,主持;
3). 深圳市海外高层次人才创新创业计划-孔雀技术创新项目,2019/03-2021/03,在研,主持;
4). 深圳大学,青年教师科研启动项目,2020/01-2022/12,在研,主持。
组内成员:
博士后
2018-2021 Srinivas Bitta Thirumalavenkata,有机化学,印度化学技术研究所(Indian Institute of Chemical Technology, Hyderabad)
2019-2021 韩明亮,有机化学,南开大学
2019-2021 赵龙,有机化学,德国亚琛工业大学(RWTH Aachen University)
2019-2021 Farid Ahmed, 超分子化学,巴基斯坦卡拉奇大学(Karachi University)
2020-2022 Shahzad Iqbal,核酸化学,四川大学
2021-2023 Jabrane Jouha,有机化学,法国奥尔良大学(University of Orléans)
2021-2023 裴海翔,生物化学与分子生物学,华东师范大学
Alumni 博士后
2018-2020 Chandrasekar Selvaraj,有机化学,印度理工学院Madras分校(Indian Institute of Technology,Madras)
2018-2020 肖秋芸,微生物,华中科技大学
研究生
赵烜,化学,2018级
曾雅婷,生命健康与环境,2021级
本科生
徐浩然,2015-2019 澳大利亚留学
刘姿含,2016-2020 瑞典留学
杨鑫晨,2016-2020
陈瀚,2016-2020
戴嘉宇,2018-2022
发表论文(2016年-至今)
7. Shahzad Iqbala,b, Farid Ahmeda and Hai Xiong*. Responsive-DNA hydrogel based intelligent materials: Preparation and applications. 2021, Submitted
6. Qiuyun Xiao, Xuan Zhao, Hai Xiong*. Biocompatible and noncytotoxic nucleoside-based AIEgens sensor for lighting-up nucleic acids. 2021, under review
5. Ming-Liang Han, Wei Huang, Yu-Wen Liu, Min Liu, Hui Xu*, Hai Xiong*, and Hui-Xiong Dai*. Pd-Catalyzed Asymmetric Dearomatization of Indoles via 2 Decarbonylative Heck-Type Reaction of Thioesters. Organic Letters 2020, DOI: org/10.1021/acs.orglett.0c03897
4. Xuan Zhao, Long Zhao, Qiuyun Xiao, Hai Xiong*, Intermolecular hydrogen-bond interaction to promote thermoreversible 2'-deoxyuridine-based AIE-organogels. Chinese Chemical Letters 2020, DOI: 10.1016/j.cclet.2020.10.008
3. Farid Ahmed and Hai Xiong*, Recent developments in 1,2,3-triazole-based chemosensors. Dyes and Pigments 2021, 185, 108905.
2. Farid Ahmed, Humaira Kabir, Hai Xiong*, Dual Colorimetric Sensor for Hg2+/Pb2+ and an Efficient Catalyst Based on Silver Nanoparticles Mediating by the Root Extract of Bistorta Amplexicaulis. Frontiers in Chemistry 2020, DOI: 10.3389/fchem.2020.591958
1. Qiuyun Xiao, Han Cheng, Zihan Liu and Hai Xiong*, Multiple Site-specific One-Pot Synthesis of Two Proteins by the Bio-orthogonal Flexizyme System. Frontiers in Bioengineering and Biotechnology 2020, 8(37), 1-6.
中国专利(2016年-至今)
1.熊海*,肖秋芸,赵烜,“一种蛋白修饰的方法”,中国专利,专利号:2019106243635;申请日:2019.07.11
2.熊海*,赵烜,肖秋芸,“TPE-2’-脱氧核苷、荧光凝胶及其制备方法与应用”,中国专利,专利号:201911244688.7;申请日:2019.12.07
3.熊海*,肖秋芸,赵烜,“一种核酸识别的AIE探针及其制备方法与应用” ,中国专利,专利号:202010830904.2;申请日:2020.08.18
部分发表论文(2004-2016年)
H. Xiong, N. Reynolds, C. Fan, M. Englert, D. Hoyer, S. Miller and D. Söll*, Dual Genetic Encoding of Acetyl-lysine and Non-deacetylatable Thioacetyl-lysine Mediated by Flexizyme. Angew. Chem. Int. Ed. 2016, 55, 4083-4086.
C. Fan*, H. Xiong, N. Reynolds and D. Söll*, Rationally evolving tRNAPyl for efficient incorporation of noncanonical amino acids. Nucleic Acid Research. 2015, 43(22): e156
H. Xiong and F. Seela*, Cross-Linked DNA: Site Selective “Click” Ligation in Duplexes with Bis-Azides and Stability Changes Caused by Internal Cross-Links. Bioconjugate Chem., 2012, 23, 1230-1243.
H. Xiong, P. Leonard and F. Seela*, Construction and Assembly of Branched Y-shaped DNA: “Click” Chemistry Performed on Dendronized 8-Aza-7-deazaguanine. Oligonucleotides. Bioconjugate Chem., 2012, 23, 856-870.
H. Xiong and F. Seela*, Stepwise “Click” Chemistry for the Template Independent Construction of a Broad Variety of Cross-linked Oligonucleotides: Influence of Linker Length, Position and Linking Number on DNA Duplex Stability. J. Org. Chem., 2011, 76, 5584-5597.
G. Qing, H. Xiong (Co-first authors), F. Seela*a and T. Sun*b, Spatially Controlled DNA Nano-patterns by “Click” Chemistry Using Oligonucleotides with Different Anchoring Sites. J. Am. Chem. Soc., 2010, 132, 15228-15232.
H. Xiong, F. Shi, J. Peng and Y. Deng*, Synthesis of supported gold catalysts for selective oxidation of cyclohexane with air. Chin. J. Mol. Catal., 2005, 19(3), 204-207.
H. Xiong, F. Shi and Y. Deng*, Synthesis and application of supported cobalt catalyst for selective oxidation of cyclohexane and toluene. Chin. J. Catal., 2004, 25(11), 887-891.