学院简介

    深圳大学高等研究院是深圳大学新成立的一个包含本科与研究生培养、侧重跨学科教学与研究的校内综合办学单位。作为深圳大学内部探索全面改革创新的学术特区,高等研究院与香港和海外著名高校合作,借鉴国外研究型大学通行的管理模式,引进具有一流视野的资深教授和发展潜力的青年教师,营造与国际接轨的学术氛围和培养环境,开展卓越的教学、研究和管理工作。 ······

本科生课程

黄方平

免疫学高级讲师

电邮: fphuang@szu.edu.cn; fphuang@hku.hk

办公室电话: +86-755-26931983

 

教育背景:

1994年:免疫学博士(英国格拉斯哥大学)

1990年:大学教育及管理学硕士(英国格拉斯哥大学)

1989年:生化病理学硕士(英国格拉斯哥大学)

1982年:医学本科学士(汕头大学医学院)

 

工作经历:

2017.06-至今   免疫学荣誉副教授   香港大学,李嘉诚医学院

2014.06-2017.06  免疫学副教授     香港大学,李嘉诚医学院

2007.06-2014.06  免疫学高级讲师(免疫学分科负责人)伦敦帝国理工医学院

2000.11-2007.06  助理教授(免疫学课负责人)  香港大学,李嘉诚医学院

1997.07-2000.11  免疫学博士后研究员     牛津大学,威廉.丹病理学院

1993.12-1997.06  免疫学博士后研究员     格拉斯哥大学,医学院免疫系

1990.07-1993.11  免疫学科研及教学助理(兼职)格拉斯哥大学,医学院免疫系

1983.01-1987.11  临床医生  汕头大学医学院,第一附属医院

 

其他学术兼职,奖励及荣誉:

•Li Ka-Shing Academic Foundation Scholarship (1987 - 1990, Shantou/Glasgow)

•MacFeat Bequest PhD Scholarship (1990 - 1993, University of Glasgow)

•Zeneca Science-Link 94 UK Outstanding Young Scientist (1994 UK)

•Edward Penley Abraham Research Fund, Oxford University (2000 Oxford)

•University of Hong Kong Research Committee Merit Awards (2003, 2004, 2006)

•Inclusion in the IBC “2000 Outstanding Intellectuals of the 21st Century” published by the International Biographical Centre, Cambridge (2006)

•Imperial College Research Excellence Award (Team Member, 2009 UK)

•Journal Editorships(编委):

 oFrontiers in Immunology

   •Associate Editor (2015 – Present): Specialty: Cancer Immunity & Immunotherapy  https://loop.frontiersin.org/people/82856/overview

   •Topic Editor (2013-14): Tumor Immunology https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231976/

 oEuropean Journal of Immunology (Editorial Board Member, 2007 - 2012)http://onlinelibrary.wiley.com/doi/10.1002/eji.201290005/pdf

 oJournal of Leukocyte Biology (Consulting Editor, 2007) http://www.jleukbio.org/content/94/1/203.full.pdf

 oClinical & Developmental Immunology (Guest Editor, 2009 - 2010) http://www.hindawi.com/journals/cdi/2011/681956/ref/

 oWorld Journal of Vaccines (Editorial Board Member, 2011 - Present) http://www.scirp.org/journal/wjv/

 oWorld Journal of Immunology (Editorial Board Member, 2011 - Present) http://www.wjgnet.com/2219-2824/edboard.htm

 oAsian Council of Science Editors (Board Member, 2014 - Present) http://theacse.com/newmembers.php?pageNum_Recordset1=33&totalRows_Recordset1=351

 oEuropean Journal of Health (Editorial Board Member, 2014 - Present)http://scik.org/index.php/ejh/announcement/view/27

 oMadridge Journal of Vaccines (Editorial Board Member, 2016 – Present)http://madridge.org/journal-of-vaccines/editors.php

•Book Editor (专科书编辑):

 oFrontiers Media SA. (Frontiers Research Topic eBook Editor, 2017) http://www.frontiersin.org/books/Autoimmuno-AntiTumour_Immunity_AATI__Understanding_the_Immune_Responses_against_Self__Altere/1201#nogo

 oInTech OA Publisher (Academic Editor, 2010)http://www.intechopen.com/editorials/42618

•Reviewer (审稿编辑) for many international scientific journals & funding bodies.

 

科研兴趣 :

•自身免疫学机理

•肿瘤免疫学机理

•树状突细胞生物免疫学机理

•调节性T和B细胞生物免疫学机理

•诱导性多能干细胞及其肿瘤免疫学方面的应用

 

已发表论文,专业书籍及国际专利(*通讯作者):

 

Journal Publications (学术期刊论文):

•*Huang FP, Stott DI. Restoration of an early, progressive defect in responsiveness to T-cell activation in lupus mice by exogenous IL-2. Autoimmunity. 1993;15(1):19-29. PMID: 8218827

•Wei XQ, Charles IG, Smith A, Ure J, Feng GJ, Huang FP, Xu D, Muller W, Moncada S, Liew FY. Altered immune responses in mice lacking inducible nitric oxide synthase. Nature. 1995 Jun 1;375(6530):408-11. PMID: 7539113

•*Huang FP, Stott DI. Dual inhibitory and stimulatory activities in serum from SLE patients and lupus mice that regulate the proliferation of an IL-2-dependent T cell line. Lupus. 1995 Aug;4(4):297-303. PMID: 8528227

•McInnes IB, al-Mughales J, Field M, Leung BP, Huang FP, Dixon R, Sturrock RD, Wilkinson PC, Liew FY. The role of interleukin-15 in T-cell migration and activation in rheumatoid arthritis. Nature Medicine 1996 Feb;2(2):175-82. PMID: 8574962

•Huang FP, Feng GJ, Lindop G, Stott DI, Liew FY. The role of interleukin 12 and nitric oxide in the development of spontaneous autoimmune disease in MRL/MP-lpr/lpr mice. J Exp Med. 1996 Apr 1;183(4):1447-59. PMID: 8666903

•McInnes IB, Leung BP, Field M, Wei XQ, Huang FP, Sturrock RD, Kinninmonth A, Weidner J, Mumford R, Liew FY. Production of nitric oxide in the synovial membrane of rheumatoid and osteoarthritis patients. J Exp Med. 1996 Oct 1;184(4):1519-24. PMID: 8879223

•Huggins ML, Huang FP, Xu D, Lindop G, Stott DI. Modulation of the autoimmune response in lupus mice by oral administration of attenuated Salmonella typhimurium expressing the IL-2 and TGF-beta genes. Ann N Y Acad Sci. 1997 Apr 5;815:499-502. PMID: 9186709

•Casey JJ, Wei XQ, Orr DJ, Gracie JA, Huang FP, Bolton EM, Liew FY, Bradley JA. Skin allograft rejection in mice lacking inducible nitric oxide synthase. Transplantation. 1997 Aug 27;64(4):589-93. PMID: 9293870

•Xu D, Chan WL, Leung BP, Huang FP, Wheeler R, Piedrafita D, Robinson JH, Liew FY. Selective expression of a stable cell surface molecule on type 2 but not type 1 helper T cells. J Exp Med. 1998 Mar 2;187(5):787-94. PMID: 9480988

•MacLean A, Wei XQ, Huang FP, Al-Alem UA, Chan WL, Liew FY. Mice lacking inducible nitric-oxide synthase are more susceptible to herpes simplex virus infection despite enhanced Th1 cell responses. J Gen Virol. 1998 Apr;79 ( Pt 4):825-30. PMID: 9568978

•Huang FP, Xu D, Esfandiari EO, Sands W, Wei XQ, Liew FY. Mice defective in Fas are highly susceptible to Leishmania major infection despite elevated IL-12 synthesis, strong Th1 responses, and enhanced nitric oxide production. J Immunol. 1998 May 1;160(9):4143-7. PMID: 9574511

•Huang FP, Niedbala W, Wei XQ, Xu D, Feng GJ, Robinson JH, Lam C, Liew FY. Nitric oxide regulates Th1 cell development through the inhibition of IL-12 synthesis by macrophages. Eur J Immunol. 1998 Dec;28(12):4062-70. PMID: 9862342

•*Huang F-P, MacPherson GG. Dendritic cells, mucosal immunity and peripheral tolerance. Mucosal Immunology Update, 1999; 7:11-15 (Review). http://www.socmucimm.org/wp-content/uploads/2014/05/Volume-7-Issue-2.pdf

•Huggins ML, Huang FP, Xu D, Lindop G, Stott DI. Modulation of autoimmune disease in the MRL-lpr/lpr mouse by IL-2 and TGF-beta1 gene therapy using attenuated Salmonella typhimurium as gene carrier. Lupus. 1999;8(1):29-38. PMID: 10025597

•Huang FP, Platt N, Wykes M, Major JR, Powell TJ, Jenkins CD, MacPherson GG. A discrete subpopulation of dendritic cells transports apoptotic intestinal epithelial cells to T cell areas of mesenteric lymph nodes. J Exp Med. 2000 Feb 7;191(3):435-44. PMID: 10662789

•*Huang FP, MacPherson GG. Continuing education of the immune system--dendritic cells, immune regulation and tolerance. Curr Mol Med. 2001 Sep;1(4):457-68. (Review). PMID: 11899090

•Esfandiari E, McInnes IB, Lindop G, Huang FP, Field M, Komai-Koma M, Wei X, Liew FY. A proinflammatory role of IL-18 in the development of spontaneous autoimmune disease. J Immunol. 2001 Nov 1;167(9):5338-47. PMID: 11673550

•Huang FP, Farquhar CF, Mabbott NA, Bruce ME, MacPherson GG. Migrating intestinal dendritic cells transport PrP(Sc) from the gut. J Gen Virol. 2002 Jan;83(Pt 1):267-71. PMID: 11752724

•Wong OH, Huang FP, Chiang AK. Differential responses of cord and adult blood-derived dendritic cells to dying cells. Immunology. 2005 Sep;116(1):13-20. PMID: 16108813

•*Huang FP, MacPherson GG. Dendritic cells and oral transmission of prion diseases. Adv Drug Deliv Rev. 2004 Apr 19;56(6):901-13. (Review). PMID: 15063597

•MacPherson G, Milling S, Yrlid U, Cousins L, Turnbull E, Huang FP. Uptake of antigens from the intestine by dendritic cells. Ann N Y Acad Sci. 2004 Dec;1029:75-82. Review. PMID: 15681746

•Ma L, Chan KW, Trendell-Smith NJ, Wu A, Tian L, Lam AC, Chan AK, Lo CK, Chik S, Ko KH, To CK, Kam SK, Li XS, Yang CH, Leung SY, Ng MH, Stott DI, MacPherson GG, *Huang FP. Systemic autoimmune disease induced by dendritic cells that have captured necrotic but not apoptotic cells in susceptible mouse strains. Eur J Immunol. 2005 Nov;35(11):3364-75. PMID: 16224814

•Chan KY, Ching JC, Xu MS, Cheung AN, Yip SP, Yam LY, Lai ST, Chu CM, Wong AT, Song YQ, Huang FP, Liu W, Chung PH, Leung GM, Chow EY, Chan EY, Chan JC, Ngan HY, Tam P, Chan LC, Sham P, Chan VS, Peiris M, Lin SC, Khoo US. Association of ICAM3 genetic variant with severe acute respiratory syndrome. J Infect Dis. 2007 Jul 15;196(2):271-80. PMID: 17570115

•Chen Y, Chan VS, Zheng B, Chan KY, Xu X, To LY, Huang FP, Khoo US, Lin CL. A novel subset of putative stem/progenitor CD34+Oct-4+ cells is the major target for SARS coronavirus in human lung. J Exp Med. 2007 Oct 29;204(11):2529-36. PMID: 17923501

•Chen YX, Man K, Ling GS, Chen Y, Sun BS, Cheng Q, Wong OH, Lo CK, Ng IO, Chan LC, Lau GK, Lin CL, Huang F, *Huang FP. A crucial role for dendritic cell (DC) IL-10 in inhibiting successful DC-based immunotherapy: superior antitumor immunity against hepatocellular carcinoma evoked by DC devoid of IL-10. J Immunol. 2007 Nov 1;179(9):6009-15. PMID: 17947674

•Sun Q, Kong CT, Huang FP, Chan LC. Aberrant dendritic cell differentiation initiated by the Mll-Een fusion gene does not require leukemic transformation. J Leukoc Biol. 2008 Jan;83(1):173-80. PMID: 17895399

•Yang CH, Tian L, Ling GS, Trendell-Smith NJ, Ma L, Lo CK, Stott DI, Liew FY, *Huang FP. Immunological mechanisms and clinical implications of regulatory T cell deficiency in a systemic autoimmune disorder: roles of IL-2 versus IL-15. Eur J Immunol. 2008 Jun;38(6):1664-76. doi: 10.1002/eji.200838190. PMID: 18465774

•Xie Y, Fan J, Chen J, Huang FP, Cao B, Tam PK, Ren Y. A novel function for dendritic cell: clearance of VEGF via VEGF receptor-1. Biochem Biophys Res Commun. 2009 Mar 6;380(2):243-8. doi: 10.1016/j.bbrc.2009.01.043. PMID: 19167346

•Mok MY, Huang FP, Ip WK, Lo Y, Wong FY, Chan EY, Lam KF, Xu D. Serum levels of IL-33 and soluble ST2 and their association with disease activity in systemic lupus erythematosus. Rheumatology (Oxford). 2010 Mar;49(3):520-7. doi: 10.1093/rheumatology/kep402. PMID: 20026564

•*Huang FP, Chen YX, To CK. Guiding the "misguided" - functional conditioning of dendritic cells for the DC-based immunotherapy against tumours. Eur J Immunol. 2011 Jan;41(1):18-25. doi: 10.1002/eji.201040543. Epub 2010 Dec 9. (Review). PMID: 21182072

•Ling GS, Cook HT, Botto M, Lau YL, *Huang FP. An essential protective role of IL-10 in the immunological mechanism underlying resistance vs. susceptibility to lupus induction by dendritic cells and dying cells. Rheumatology (Oxford). 2011 Oct;50(10):1773-84. doi: 10.1093/rheumatology/ker198. PMID: 21727182

•Sun J, Li R, Guo J, Jia Y, Sun X, Liu Y, Li Y, Huang F, Lu L, Li Z. Superior molecularly altered influenza virus hemagglutinin peptide 308-317 inhibits collagen-induced arthritis by inducing CD4+ Treg cell expansion. Arthritis Rheum. 2012 Jul;64(7):2158-68. doi: 10.1002/art.34372. PMID: 22231228

•Sattler S, Smits HH, Xu D, Huang FP. The evolutionary role of the IL-33/ST2 system in host immune defence. Arch Immunol Ther Exp (Warsz). 2013 Apr;61(2):107-17. doi: 10.1007/s00005-012-0208-8. (Review). PMID: 23283516

•Sattler S, Ling GS, Xu D, Hussaarts L, Romaine A, Zhao H, Fossati-Jimack L, Malik T, Cook HT, Botto M, Lau YL, Smits HH, Liew FY, *Huang FP. IL-10-producing regulatory B cells induced by IL-33 (Breg(IL-33)) effectively attenuate mucosal inflammatory responses in the gut. J Autoimmun. 2014 May;50:107-22. doi: 10.1016/j.jaut.2014.01.032. PMID: 24491821

•*Huang FP. Therapeutic Vaccination against Cancers - A Conceptual Overview with Updates on the Immunological Approach. SM Vaccine Vaccin. 2015 Nov;1(2):1009. http://smjournals.com/vaccines/fulltext/smvvj-v1-1009.pdf

•Wang T, Sun X, Zhao J, Zhang J, Zhu H, Li C, Gao N, Jia Y, Xu D, Huang FP, Li N, Lu L, Li ZG. Regulatory T cells in rheumatoid arthritis showed increased plasticity toward Th17 but retained suppressive function in peripheral blood. Ann Rheum Dis. Ann Rheum Dis. 2015 June; 74(6):1293-301. doi: 10.1136/annrheumdis-2013-204228.

•Zhao H, Davies TJ, Ning J, Chang Y, Sachamitr P, Sattler S, Fairchild PJ, *Huang FP. A Highly Optimized Protocol for Reprogramming Cancer Cells to Pluripotency Using Non-Viral Plasmid Vectors. Cell Reprogram. 2015 Feb;17(1):7-18. doi: 10.1089/cell.2014.0046. PMID: 25549177

•*Huang FP. Autoimmuno-Anti-Tumour Immunity (AATI) – Understanding the Immune Responses against “Self” & “Altered-self”. (Frontiers in Immunology Research Topic. PMID: 25452757; PMCID: PMC4231976). Lausanne: Frontiers Media (Editorial) May 18, 2017. doi: 10.3389/978-2-88945-190-6.

•Cossarizza A et al. Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition) Eur J Immunol. 2019 Oct;49(10): 1457-1973. DOI: 10.1002/eji.201970107. PMID: 31633216

 

Books/Book Chapters (书,专书章节):

•Isolation of dendritic cells from rat lymph and spleen. By MacPherson GG, Wykes M, Huang F-P, Jenkins CD. In “Methods in Molecular Medicine: Dendritic Cell Protocols” Part I (Chapter 4). Edited by Robinson SP and Stagg AJ. Totowa, N.J.: Humana Press, 2001.

•Intestinal Dendritic Cells. By MacPherson GG, Huang F-P and Liu LM. In “Dendritic Cells (2nd ed.) Biology and Clinical Applications” (Chapter 25). Edited by Lotze MT and Thomson AW. Harcourt International Academic Press, 2001 (August).

•Uptake of antigens from the intestine by dendritic cells. Macpherson G, Milling S, Yrlid U, Cousins L, Turnbull E, Huang F-P. Uptake of antigens from the intestine by dendritic cells. In “Oral Tolerance: New Insights & Prospects for Clinical Application” (Part 2). Edited by Weiner HL, Mayer L and Strober W. Ann NY Acad Sci 2004 (December);1029:75-82. Article first published online: 12 JAN 2006. DOI: 10.1196/annals.1309.010 http://onlinelibrary.wiley.com/doi/10.1196/annals.1309.010/abstract

•Autoimmune Disorders: Current concepts & advances from bedside to the mechanistic insights. Edited by Fang-Ping Huang, ISBN 979-953-307-269-1, InTech. September 2011. http://www.intechopen.com/books/autoimmune-disorders-current-concepts-and-advances-from-bedside-to-mechanistic-insights

•Regulatory T Cell Deficiency in Systemic Autoimmune Disorders – Causal Relationship and Underlying Immunological Mechanisms. By Fang-Ping Huang and Susanne Sattler. In "Autoimmune Disorders - Pathogenetic Aspects" (Chapter 6). Edited by Clio P. Mavragani, ISBN 978-953-307-643-0, InTech, October 10, 2011

•Regulatory B Cells - Implications in Autoimmune and Allergic Disorders. By Susanne Sattler, Luciën E.P.M. van der Vlugt, Leonie Hussaarts, Hermelijn H. Smits and Fang-Ping Huang. In "Recent Advances in Immunology to Target Cancer, Inflammation and Infections" (Chapter 9). Edited by Jagat R. Kanwar, ISBN 978-953-51-0592-3, InTech, May 5, 2012

•Autoimmuno-Anti-Tumour Immunity (AATI) – Understanding the Immune Responses against “Self” & “Altered-self”. (Frontiers Research Topic ebook) Huang, F-P., ed. Lausanne: Frontiers Media. May18, 2017 ISBN: 978-2-88945-190-6; ISSN: 1664-8714; doi: 10.3389/978-2-88945-190-6 http://journal.frontiersin.org/researchtopic/1730/pdf

 

Patents filed (国际专利):

•As Primary inventor:

*Huang F-P, Chen YX, Man K. ANTI-TUMOR VACCINES DELIVERED BY DENDRITIC CELLS DEVOID OF INTERLEUKIN-10.

US Regular Patent: Ref. No.: 11/957,146, filed on Dec. 14, 2007. Publication Date: January 8, 2009, Publication No. 20090010948, US Patent & Trademark Office, USA. Website: http://www.uspto.gov/patft/index.html.

PCT patent: Ref No: WO2008/071093, filed on Dec. 17, 2007, Publication Date: June 19, 2008; WIPO's website: www.wipo.int/pctdb.

•As Co-inventor (US Provisional Patent) Tian L, Tam PKH, Huang F-P, Lamb JR. AGE DEPENDENCY OF T REGULATORY CELLS. (Ref. No.: IP00093).

 

主要科研项目及资助 (Major Research Projects/Grants Awarded):

•RGC CERG 2001-4 (PI) (HK$1,049,400) Project title: “The roles of regulatory dendritic cells in peripheral tolerance and autoimmunity”. (HKU 7246/01M)(主持,已结题)

•RGC CERG 2002-5 (PI) (HK$876,000) Project title: “Functional conditioning of dendritic cells for DC-based tumour vaccines”. (HKU 7291/02M)(主持,已结题)

•Outstanding Research Program Scheme 2002-5 (CoI) (HKU-VC-DF, HK$1,176,000) Project title: “Influenza in Southern China: the pandemic epicentre”. (ORPS 2002-5)(已结题)

•RGC CERG 2003-6 (PI) (HK$ 624,000) Project title: “Mechanisms for the Induction and Regulation of Autoimmune Responses by Dendritic Cells and T Regulatory Cells in Systemic Lupus Erythematosus”. (HKU 7410/03M)(主持,已结题)

•RGC CERG 2004-7 (PI) (HK$ 1,739,500) Project title: “Molecular characterization of dendritic cells functionally modulated by dying cells - mechanism for the induction and regulation of autoimmune responses by dendritic cells (II)”. (HKU 7397/04M)(主持,已结题)

•RGC CERG 2006-9 (PI) (HK$ 902,500) Project title: “Mechanistic assessment of autoimmune responses induced by dendritic cells in interleukine-10 deficient mice – implications in lupus pathogenesis”. (HKU 7580/06M)(主持,已结题)

•RGC GRF 2008-10 (CoI) (HK$1,086,658) Project title: “Toll-like Receptor 7 signaling and its implications on regulatory T cells in hepatitis B infection”. (HKU 766407M)(已结题)

•ARC UK 2008-13 (PI) (ARUK: £201,560; FEC: £454,288); Project title: “A Potential Role of Interleukin-33 in the Induction of Regulatory B Cells and Implications in Systemic Autoimmunity”. (ARUK 185230)(主持,已结题)

•RGC GRF 2013-16 (CoI) (HK$866,032) Project title: “The roles of IL-33 in the modulation of macrophage differentiation and immunoregulatory functions in systemic lupus erythematosus”. (HKU 775313M)(已结题)

 

其他科研项目及资助 (Other Research Projects/Grants Awarded):

•HKU CRCG 2001 (Project Grant, HK$120,000) Project title: Tracking, visualizing & characterization of normal and “auto-reactive” T and B cells in steady state & in “danger”.(主持,已结题)

•HKU CRCG 2001 (Project Grant, HK$ 98,060) Project title: “Effects of uptake of apoptotic and necrotic cells by dendritic cells (DC) on anti-nuclear antibody production in normal and in lupus prone mouse models”.(主持,已结题)

•HKU CRCG Seeding Fund 2002 (Project Grant) Project title: “The role of T regulatory cell in the long-term survival of rat small bowel allograft”.(主持,已结题)

•HKU SARS Research Fund 2003 (Project Grant) Project title: “Genetic polymorphism study of the immune response genes in relation to susceptibility, clinical outcome and treatment response of SARS”.(已结题)

•AIDS Trust Fund 2004-5 (Project Grant). Project title: Development of new technique for detection of HIV specific cytotoxic T lymphocytes (MSS 111, HKU project No. 21004112).(已结题)

•HKU CRCG 2003 (Project Grant, HK$ 120,000) Project title: “Immunotherapy by adoptive transfer of T regulatory cells in a mouse model of systemic lupus erythematosus”.(主持,已结题)

•HKU URC Merit Awards: 2006 (HK$ 50,000); 2004 (HK$ 50,000); 2003 (HK$ 50,000)

•Cheng Yu Tung Research Fund 2005-6 (CYT Visiting Research Fellow Scheme, YX Chen) Project title: “Regulatory T cells in the mouse model of hepatocellular carcinoma”.(主持,已结题)

•Pennine - Great Wall Visiting Research Fellow Scheme 2011-12 (Dr HZ Zhao, PGW Ltd Medical Research Fund, £10,000) Project title: “Functional conditioning & characterization of dendritic cells (DC) generated from induced pluripotent stem cells”.(主持,已结题)

•Tianjin Government Post-doctoral International Training Program 2012-13 (The Chinese Government Visiting Research Fellow Scheme – Dr YX Chang) Project title: “Immunomodulatory Effects of Bergapten on Dendritic Cell Functions”.(主持,已结题)

•HKU SKLLR Fund 2014 (HK$ 300,000). Project title: “Dendritic cells Tailor-made & functionally conditioned for novel tumor vaccine development against liver cancers”.(主持,已结题)

•HKU Seed Funding Program for Basic Research 2014 (HK$ 120,000) Project title: “Generation of dendritic cells from liver cancer cell-derived iPSc for novel tumor vaccine development - Part I: Reprogramming of liver cancer cells to pluripotency using non-viral plasmid vectors”.(主持,已结题)

•HKU FM Matched Fund (2015-17) (HK$ 120,000) Project title: “Reprogramming of liver cancer cells to pluripotency using non-viral plasmid vectors”.(主持,已结题)

•HKU Seed Fund for Strategic Research Theme of Cancer (SRTC) (2015-16) (HK$ 100,000) Project title: “Dendritic cells tailor-made & functionally conditioned for the development of novel immunotherapy against nasopharyngeal carcinoma (NPC) [Part I]: Reprogramming NPC Cancer Cells/Cell Lines to Pluripotency Using Non-viral Plasmid Vectors”.(主持,已结题)

•HKU DORS2015 (HK$ 60,000) Project title: “Generation & functional conditioning of dendritic cells derived from cancer stem cells for novel vaccine development against liver cancers [Part I]: Generation of the liver CSC-specific DC (CSC-iPSC-DC)”.(主持,已结题)

•HKU Seed Funding Program for Basic Research 2015-16 (HK$ 43,000) Project title: “Mechanisms & therapeutic potential of interleukin-35 in systemic autoimmune & related lymphoproliferative disorders”.(主持,已结题)

•HKU Seed Funding for Basic Research 2017 (HK$ 55,000) Project title: “In vivo tracking & visualizing the IL-10-producing regulatory B cells induced & expanded by IL-33 (BregIL-33), & following adoptive transfer of the BregIL-33 into IL-10-deficient mice”.(主持,已结题)