学院简介

    深圳大学高等研究院是深圳大学新成立的一个包含本科与研究生培养、侧重跨学科教学与研究的校内综合办学单位。作为深圳大学内部探索全面改革创新的学术特区,高等研究院与香港和海外著名高校合作,借鉴国外研究型大学通行的管理模式,引进具有一流视野的资深教授和发展潜力的青年教师,营造与国际接轨的学术氛围和培养环境,开展卓越的教学、研究和管理工作。 ······

本科生课程

曾绍雄

博士, 高级讲師

Email: jshtsang@szu.edu.cn

Office: 深圳大学办公楼341室

 

教育背景

1988 英国肯特大学 博士

1984 香港中文大学 硕士

1983 日本大阪大学, 东京大学 文憑

1980 加拿大阿尔伯塔大学 荣誉学士

 

工作经历

2016.08至 2019.04 香港大学,兼职讲師

2016.07至 2017.06 香港大学,荣誉副教授

1997.08至 2016.06 香港大学,副教授

1994.08至 1997.07 香港大学,助教授

1993.11至 1994.07 英国邓迪大学, 博士后

1987.10至 1993.10 英国牛津大学,博士后

1983.10至 1984.07 香港中文大学, 助教

1980.09至 1982.09 香港中文大学, 助教

 

荣誉和奖励:

1984-1987Recipient of an Overseas Research Scheme Award funded by the Committee of Vice-Chancellors and Principals of the Universities of the United Kingdom Recipient of a University of Kent Studentship.

1982-1983 Recipient of a postgraduate research fellowship funded by UNESCO, the ICRO and the Japanese Government.

1992 A travel/subsistence grant was provided by the Royal Society to attend the 16th International Conference on Yeast Genetics and Molecular Biology in Vienna.

1992 A bursary was provided by the Marine Biological Association of the United Kingdom (MBA) to study helix-loop-helix proteins in marine diatoms.

2006 Recipient for an Award for Teaching Excellence from the Faculty of Science.

 

学术兼职:

Life Member of the Microbiology Society, United Kingdom

Life Member of the Genetics Society, United Kingdom

 

代表性文章:

1.Tsang, J.S.H., Sallis, P.J., Bull, A.T. and Hardman, D.J.  1988.  A mono bromoacetate dehalogenase from Pseudomonas cepacia MBA4.  Arch. Microbiol. 150, 441 446.

2.Chambers, A., Tsang, J.S.H., Stanway, C., Kingsman, A.J. and Kingsman, S.M.  1989.  Transcriptional control of Saccharomyces cerevisiae PGK gene by RAP1.  Molec. Cell. Biol. 9, 5516 5524.

3.Henry, Y.A.L., Chambers, A., Tsang, J.S.H., Kingsman, A.J. and Kingsman, S.M.  1990.  Characterisation of the DNA binding domain of the yeast RAP1 protein.  Nucleic Acids Res. 18, 2617 2623.

4.Chambers, A., Stanway, C., Tsang, J.S.H., Henry, Y.A.L, Kingsman, A.J. and Kingsman, S.M.  1990.  ARS binding factor 1 binds adjacent to RAP1 at the UASs of the yeast glycolytic genes PGK and PYK1. Nucleic Acids Res. 18, 5393 5399.

5.Tsang, J.S.H., Henry, Y.A.L., Chambers, A., Kingsman, A.J. and Kingsman, S.M. 1990.  Phosphorylation influences the binding of the yeast RAP1 protein to the UAS of the PGK gene.  Nucleic Acid Res. 18, 7331 7337.

6.Murdiyatmo, U., Asmara, W., Tsang, J.S.H., Baines, A.J., Bull, A.T. and Hardman, D.J.  1992.  Molecular biology of the 2 haloacid halidohydrolase IVa from Pseudomonas cepacia MBA4.  Biochem. J. 284, 87 93.

7.Dowell, S.J., Tsang, J.S.H. and Mellor, J.  1992.  The centromere and promoter factor 1 of yeast contains a dimerisation domain located carboxy terminal to the bHLH domain.   Nucleic Acids Res. 20, 4229 4236.

8.Kent, N.A., Tsang, J.S.H., Crowther, D.J. and Mellor, J. 1994.  Chromatin structure modulation in Saccharomyces cerevisiae by centromere and promoter factor 1.  Molec. Cell. Biol. 14, 5229 5241.

9.Kong, K.F. and Tsang, J.S.H.  1998. Nucleotide sequences of cDNAs (AJ010160, AJ010161 and AJ010162) encoding a Type 2 metallothionein-like protein from water hyacinth Eichhornia crassipes.  Plant Physiol 118: 1101.

10.Kong, K.F. and Tsang, J.S.H.  1999. Nucleotide sequences of genomic clones (Accession nos. AJ247090, AJ247195 and AJ247196) encoding a type 2 metallothionein-like protein from water hyacinth Eichhornia crassipes.  Plant Physiol 120:1207.

11.Tsang, J.S.H. and Sam, L.  1999. Cloning and characterization of a cryptic haloacid dehalogenase gene from Burkholderia cepacia MBA4.  J. Bacteriol. 181:6003-6009.

12.Tsang, J.S.H. and Pang, B.C.M.  2000. Identification of the dimerization domain of dehalogenase IVa of Burkholderia cepacia MBA4.  Appl. Environ. Microbiol. 66:3180-3186.

13.Pang, B.C.M and Tsang J.S.H. 2001. Mutagenic analysis of the conserved residues in dehalogenase IVa of Burkholderia cepacia MBA4.  FEMS Microbiol. Lett. 204:135-140.

14.Tsang, J.S.H. and Sze, J. 2002. Sec-dependent and Sec-independent translocation of haloacid dehalogenase Chd1 of Burkholderia cepacia MBA4 in Escherichia coli. FEMS Microbiol. Lett. 211:259-264.

15.Tsang, J.S.H. 2004. Molecular biology of the Burkholderia cepacia complex.  Adv. Appl. Microbiol. 54: 71-91.

16.Schmidberger, J.W., Oakley, A.J., Tsang, J.S.H. and Wilce, M.C.J.  2005. Purification, crystallization and preliminary crystallographic analysis of DehIVa, a dehalogenase from Burkholderia cepacia MBA4. Acta Cryst. F 61:271-273.

17.Chan, Y.H., Kwok, A.C.M., Tsang,J.S.H. and Wong, J.T.Y. 2006. Alveolata histone-like proteins have different evolutionary origins. J. Evol. Biol. 19:1717-1721.

18.Yu, M. and Tsang, J.S.H. 2006. Use of ribosomal promoters from Burkholderia cenocepacia and Burkholderia cepacia for improved expression of transporter protein in Escherichia coli.  Protein Exp. Purif. 49:219-227.

19.Kwok, C.S.Y., Siu, A.F-M., Ngai,S.M., Che, C-M. and Tsang, J.S.H. 2007. Proteomic analysis of Burkholderia cepacia MBA4 in the degradation of monochloroacetate. Proteomics 7:1107-1116.

20.Schmidberger J.W., Wilce J.A., Tsang J.S.H. and Wilce M.C.J. 2007. Crystal structures of the substrate free-enzyme, and reaction intermediate of the HAD superfamily member, haloacid dehalogenase DehIVa from Burkholderia cepacia MBA4. J. Mol. Biol. 368:706-717.

21.Faan, Y-W., Yu, M. and Tsang, J.S.H. 2007. Blue-white selection of regulatory genes that affect the expression of dehalogenase IVa of Burkholderia cepacia MBA4. Appl. Microbiol. Biotech. 76:429-437.

22.Yu, M., Faan, Y-W., Chung, W.Y.K. and Tsang, J.S.H.  2007. Isolation and characterization of a novel haloacid permease from Burkholderia cepacia MBA4.  Appl. Environ. Microbiol. 73:4874-4880.

23.Ho, P., Kong, K.F., Chan, Y.H., Tsang, J.S.H. and Wong, J.T.Y. 2007. An unusual S-adenosylmethionine synthetase gene from dinoflagellates is methylated. BMC Molecular Biology 8:87.

24.Yeung, S-L., Cheng, C., Lui, T.K.O., Tsang, J.S.H., Chan, W-T. and Lim, B.L. 2009. Purple acid phosphatase-like sequences in prokaryotic genomes and the characterization of an atypical purple alkaline phosphatase from Burkholderia cenocepacia J2315. Gene 440:1-8.

25.Tse, Y.M., Yu, M and Tsang, J.S.H. 2009. Topological analysis of a haloacid permease of a Burkholderia sp. bacterium with a PhoA-LacZ reporter. BMC Microbiology 9:233.

26.Su, X., Kong, K-F. and Tsang J.S.H. 2012. Transports of acetate and haloacetate in Burkholderia species MBA4 are operated by distinct systems. BMC Microbiology 12:267.

27.Su, X. and Tsang, J.S.H. 2013. Existence of a robust haloacid transport system in a Burkholderia species bacterium. BBA-Biomembranes 1828(2):187–192.

28.Su, X., Deng, L., Kong, K.F. and Tsang J.S.H. 2013. Enhanced degradation of haloacid by heterologous expression in related Burkholderia species. Biotechnol. Bioeng. 110(10): 2687-2696.

29.Pan, Y., Kong, K.F. and Tsang, J.S.H. 2014. Draft genome sequence of the haloacid-degrading Burkholderia caribensis strain MBA4. Genome Announcements 2(1):e00047-14.

30.Pan, Y., Kong, K.F. and Tsang, J.S.H. 2015. Complete genome sequence and characterization of the haloacid-degrading Burkholderia caribensis MBA4. Standards in Genomic Sciences 10:114.

31.Pan, Y., Kong, K.F. and Tsang, J.S.H. 2016. Complete genome sequence of the exopolysaccharide-producing Burkholderia caribensis type strain MWAP64. Genome Announcements 4(1):e01636-15. doi:10.1128/genomeA.01636-15.

32.Su, X., Li, R. and Tsang J.S.H. 2016. The 228 bp upstream non-coding region of haloacids transporter gene dehp2 has regulated promoter activity. Gene 593:322-329.

33.Su, X., Li, R. and Tsang J.S.H. 2016. Transport of haloacids across biological membranes. BBA-Biomembranes 1858:3061-3070.