Understandingasymmetric catalysis by computational chemistry
Prof. Eric A. B.Kantchev
Green Chemistry Group Leader, Schoolof Chemistry and Chemical Engineering , Hefei University of Technology
About the Speaker
Prof. Eric A. B.Kantchev obtained his undergraduate degree (1996) in organic and analyticalchemistry from the University of Sofia in his native Bulgaria. Having completeda Ph. D. (2001) at Ohio State University, Columbus, OH (USA) and twopostdoctoral appointments, in Academia Sinica, Taipei (Taiwan, 2001-2004) andYork University, Toronto, ON (Canada; 2004-2005), he began his career as aresearch scientist in A*STAR, Singapore (2005-2013). After shortterm stints in School of Materials Science and Engineering, NanyangTechnologcal University, Singapore (2013-2014) and School of Chemistry,Chemical Engineering and Life Science, Wuhan University of Technology (China,2014), Prof. Kantchev is currently Green Chemistry Group Leader at the Schoolof Chemistry and Chemical Engineering, Hefei University of Technology, China.Prof. Kantchev has participated in a number of projects in wide range ofchemical problems, from carbohydrate-covered dendrimers to organometallics, anddensity functional theory calculations to conducting polymers. Currently, hisresearch interests lie in computational chemistry studies of transition metalcatalysts and their reactions. Since 1999, the results of these efforts havebeen published in 51 peer-reviewed publications gathering total of >3100citations (h index = 21).
Talk Introduction
Chiral compounds areof great interest to society due to their use for manufacturing ofpharmaceuticals. Among various methods for making such chemicals, asymmetriccatalysis is conceptually the most advanced because it also imparts syntheticefficiency and environmental friendliness to the process. Computational studieshave the potential to reveal important details for the nature of theenantioselection process and aid new ligand design. In this lecture, the whyand how of using quantum chemical calculations to understand enantioselectivitywill be discussed. In the second part, the application of this approach to theRh-catalyzed asymmetric 1,4-addition, one of the most important catalyticasymmetric C-C bond forming reactions, will be presented.
时间：2016年11月30号下午15:00-16:00
地点：科技楼二号报告厅
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