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XIONG Hai

Ph.D, Research Scientist

hai.xiong#szu.edu.cn

Zhizhi Building

Eductation

2006-2012 Ph.D, Osnabrück University, and Center for Nanotechnology ( CeNTech )of Münster University, Germany.

2001-2004 Master, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences

1997-2001 Bachelor , Nanchang University


Previous Positions/Employment

2012-2016 Postdoctoral Associate,School of medicine, Yale University

2004-2006 Research Assistant,Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences


Research Interests

Non-natural nucleic acids: Chemical modification and functionalization

DNAaptameranditsapplication

Fluorescence molecular probe

Fabrication of DNA self-assembled nanostructures

Synthesis of nano Medical and Biomaterials

The construction of 2D smart materials and non-natural nucleic acids: the application of biosensor and delivery of medicines

Site-specific noncanonical amino acids and protein post-translational modification


Honor

2020 Outstanding Undergraduate Teacher Award

2022 Excellent Reviewer of “SCIENTIA SINICA Chimica”

2018 Pearl River plan-young Talents in Guangdong province

2017 High-Level Talents in Nanshan District of Shenzhen

2016 Overseas High-Caliber Personnel (Peacock Plan)



Academic service

Chinese Chemical Letters: Young Editorial Members

Frontiers in Bioengineering and Biotechnology:Lead Guest Editor

Hehadpublished nearly 50 articles, such as  J. Am. Chem. Soc., Angew. Chem. Int. Ed., Coordination Chemistry Reviews ., TrAc-Trends in Anal. Chem., Nucleic Acid Res., Anal . Chem ., Chem. Eng. J., Small., ACS Sensors., Bioactive Materials., Org. Lett., Anal. Chim. Acta., Talanta., Chin. Chem. Lett., Environ. Sci: Nano., Journal of Materials Chemistry B., Bioorganic Chem., Dyes and Pigments., Bioconjugate Chem., J. Org. Chem., etc.


Publications (Independent Corresponding author/First author, CAS: Scientific Journal Ranking Q1)

21.Saima Hameed, Sumaira Sharif, Muhammad Ovais, and Hai Xiong*, Emerging Trends and Future Challenges of Advanced 2D Nanomaterials for Combating Bacterial Resistance. Bioactive Materials , 2024 , 38, 225–257.

20.Yating Zeng, Ziyan Wang, Linyu Zeng, and Hai Xiong*, Enhancing or Quenching of a Mitochondria-Targeted AIEgens-Floxuridine Sensor by the Regulation of pH-Dependent Self-assembly, Efficient Recognition of Hg2+, and Stimulated Response of GSH. Analytic Chemistry , 2023 , 95, 18880−18888.

19.Farid Ahmed, Weiqing Xu, Muhammad Muzammal Hussain, Waheed Ullah Khan and Hai Xiong*,Bioimaging-guided Discrimination of Normal/Cancer Cells and Bacteria using Ag+-Mediated Red Fluorescent Carbon Dots. Chemical Engineering Journal , 2023 ,477, 147300.

18. Hai Xiong*, Fengli Li, Linyu Zeng, and Qiyu Lei, Recent and Emerging Trends of DNA/RNA Hybridized COF Nanoprobes for Analytes Detection and Biomarkers Imaging in Clinical Biomedicines. Trends in Analytical Chemistry , 2024 ,170, 117414.

17. Yating Zeng, Saima Hameed, Hai Xiong*,Multifunctional nucleoside-AIEgens bearing quaternary ammonium cationic for reversible detection, bioimaging and antibacterial. Analytica Chimica Acta , 2023 , 1283, 341924.

16. Farid Ahmed, Muhammad Muzammal Hussain, Waheed Ullah Khan, and Hai Xiong*, Exploring Recent Advancements and Future Prospects on Coordination Self-Assembly of the Regulated Lanthanide-Doped Luminescent Supramolecular Hydrogels. Coordination Chemistry Reviews , 202 4 ,499, 215486.

15.Waheed Ullah Khan, Muhammad Muzammal Hussain, Farid Ahamd and Hai Xiong*,A review of the growing trend towards heteroatoms-doped carbon dots based on dopamine acting as a hybrid agent and detected analyte. Talanta , 2023 , 265, 124781.

14.Muhammad Muzammal Hussain, Waheed Ullah Khan, Farid Ahmed, and Hai Xiong*,Recent developments of Red/NIR-CDs in biosensing, bioimaging, and tumor theranostics. Chemical Engineering Journal , 2023 , 465, 143010.

13.Weiqing Xu, Farid Ahmed, and Hai Xiong*,A mitochondria-targeted fluorescent probe based on biocompatibleRBH-Ufor theenhanced responseofFe3+in living cells and quenching ofCu2+in vitro. Analytica Chimica Acta , 2023 ,1249, 340925.

12.Long Zhao, Farid Ahmed, Yating Zeng, Weiqing Xu, and Hai Xiong*,Recent Developments in G‑Quadruplex Binding Ligands and Specific Beacons on Smart Fluorescent Sensor for Targeting Metal Ions and Biological Analytes. ACS Sensors, 2022 , 7, 2833−2856.

11.Farid Ahmed, Shahzad Iqbal, and Hai Xiong*,Multifunctional Dual Emissive Fluorescent Probe Based on Europium-doped Carbon Dots (Eu-TCA/NCDs) for Highly Selective Detection of Chloramphenicol, Hg2+and Fe3+. Environmental Science-Nano , 2022 ,9, 2624-2637.(正封面文章)

10.Long Zhao, Farid Ahmed, and Hai Xiong*,An excimer ‘ON –OFF’ switch based on telomeric G-quadruplex and rGO for trace thrombin detection. Chinese Chemical Letters , 2022 ,33, 4243–4247.

9.Jabrane Jouha, and Hai Xiong*, DNAzyme-Functionalized nanomaterials: Recent Preparation, Current Applications, and Future Challenges. Small , 2021 , 17, 2105439.(封面文章)

8.Farid Ahmed, Shahzad Iqbal, Long Zhao, and Hai Xiong *,“ON-OFF-ON” fluorescence switches based on N,S-doped carbon dots: Facile hydrothermal growth, selective detection of Hg2+, and as a reversive probe for guanine. Analytica Chimica Acta , 2021 , 1183, 338977.

7. Shahzad Iqbal, Farid Ahmed, and Hai Xiong *, Responsive-DNA hydrogel based intelligent materials: Preparation and applications. Chemical Engineering Journal , 2021 , 420, 130384.

6. Qiuyun Xiao, Xuan Zhao, and Hai Xiong *, Biocompatible and noncytotoxic nucleoside-based AIEgens sensor for lighting-up nucleic acids. Chinese Chemical Letters , 2021 ,32, 1687–1690. (正封面文章)

5. Xuan Zhao, Long Zhao, Qiuyun Xiao, and Hai Xiong *, Intermolecular hydrogen-bond interaction to promote thermoreversible 2'-deoxyuridine-based AIE-organogels. Chinese Chemical Letters , 2021 , 32, 1363–1366.

4. Farid Ahmed, and Hai Xiong*, Recent developments in 1,2,3-triazole-based chemosensors. Dyes and Pigments , 2021 , 185, 108905.

3. H. Xiong , N. Reynolds, C. Fan, M. Englert, D. Hoyer, S. Miller and D. Söll*, Dual Genetic Encoding of Acetyl-lysine and Non-deacetylatable Thioacetyl-lysine Mediated by Flexizyme. Angew. Chem. Int. Ed. 2016 ,55, 4083-4086.

2.G. Qing#, H. Xiong# (Co-first authors), F. Seela* and T. Sun*, Spatially Controlled DNA Nano-patterns by “Click” Chemistry Using Oligonucleotides with Different Anchoring Sites. J. Am. Chem. Soc. , 2010 , 132 , 15228-15232.

1. H. Xiong , F. Shi and Y. Deng*,Synthesis and application of supported cobalt catalyst for selective oxidation of cyclohexane and toluene. Chin. J. Catal. , 2004 , 25 (11), 887-891.


Book-Chapter

SPRINGER NATURE: Book entitled “Metal,Metal-Oxides andMetalSulfides forBatteries,FuelCells,SolarCells, Photocatalysis and Health Sensors” 2021 ,ISBN 978-3-030-63791-0 (eBook)

Chapter 8:Developing Trends in DNA Biosensor and Their Applications---Chandrasekar Selvaraj, Srinivas Bitta Thirumalavenkata and Hai Xiong*---


Address: Institute for Advanced Study

Shenzhen University

Nanshan District

Shenzhen, Guangdong

China 518060

Tel: +86-755-2649-2572

CopyRight@Institute for Advanced Study,Shenzhen University.