Eductation
2006-2012 Ph.D, Osnabrück University, and Center for Nanotechnology (CeNTech)of Münster University, Germany.
2001-2004 Master, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences
1997-2001 Bachelor,Nanchang University
Previous Positions/Employment
2012-2016 Postdoctoral Associate, School of medicine, Yale University
2004-2006 Research Assistant, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences
Research Interests
Non-natural nucleic acids: Chemical modification and functionalization
DNA aptamer and its application
Fluorescence molecular probe
Fabrication of DNA self-assembled nanostructures
Synthesis of nano Medical and Biomaterials
The construction of 2D smart materials and non-natural nucleic acids: the application of biosensor and delivery of medicines
Site-specific noncanonical amino acids and protein post-translational modification
Honor：
2020 Outstanding Undergraduate Teacher Award
2022 Excellent Reviewer of “SCIENTIA SINICA Chimica”
2018 Pearl River plan-young Talents in Guangdong province
2017 High-Level Talents in Nanshan District of Shenzhen
2016 Overseas High-Caliber Personnel (Peacock Plan)
Academic service：
Chinese Chemical Letters: Young Editorial Members
Frontiers in Bioengineering and Biotechnology: Lead Guest Editor
He had published nearly 50 articles, such asJ. Am. Chem. Soc., Angew. Chem. Int. Ed.,Coordination Chemistry Reviews.,TrAc-Trends in Anal. Chem., Nucleic Acid Res., Anal. Chem., Chem. Eng. J., Small., ACS Sensors., Org. Lett., Anal. Chim. Acta., Talanta., Chin. Chem. Lett., Environ. Sci: Nano., Journal of Materials Chemistry B., Bioorganic Chem., Dyes and Pigments., Bioconjugate Chem., J. Org. Chem.,etc.
Publications ( Independent Corresponding author/ First author, CAS: Scientific Journal Ranking Q1)
21.Yating Zeng, Ziyan Wang, Linyu Zeng, and Hai Xiong*, Enhancing or Quenching of a Mitochondria-Targeted AIEgens-Floxuridine Sensor by the Regulation of pH-Dependent Self-assembly, Efficient Recognition of Hg2+, and Stimulated Response of GSH.Analytic Chemistry, 2023, doi.org/10.1021/acs.analchem.3c04415.
20.Farid Ahmed, Weiqing Xu, Muhammad Muzammal Hussain, Waheed Ullah Khan, and Hai Xiong*,Bioimaging-guided Discrimination of Normal/Cancer Cells and Bacteria using Ag+-Mediated Red Fluorescent Carbon Dots.Chemical Engineering Journal, 2023,477, 147300.
19. Hai Xiong*, Fengli Li, Linyu Zeng, and Qiyu Lei, Recent and Emerging Trends of DNA/RNA Hybridized COF Nanoprobes for Analytes Detection and Biomarkers Imaging in Clinical Biomedicines.Trends in Analytical Chemistry, 2024,170, 117414.
18. Yating Zeng, Saima Hameed, and Hai Xiong*,Multifunctional nucleoside-AIEgens bearing quaternary ammonium cationic for reversible detection, bioimaging and antibacterial.Analytica Chimica Acta, 2023, 1283, 341924.
17. Farid Ahmed, Muhammad Muzammal Hussain, Waheed Ullah Khan, and Hai Xiong*, Exploring Recent Advancements and Future Prospects on Coordination Self-Assembly of the Regulated Lanthanide-Doped Luminescent Supramolecular Hydrogels.Coordination Chemistry Reviews, 202 4,499, 215486.
16.Waheed Ullah Khan, Muhammad Muzammal Hussain, Farid Ahamd and Hai Xiong*,A review of the growing trend towards heteroatoms-doped carbon dots based on dopamine acting as a hybrid agent and detected analyte.Talanta, 2023, 265, 124781.
15.Muhammad Muzammal Hussain, Waheed Ullah Khan, Farid Ahmed, and Hai Xiong*,Recent developments of Red/NIR-CDs in biosensing, bioimaging, and tumor theranostics.Chemical Engineering Journal, 2023,465, 143010.
14.Weiqing Xu, Farid Ahmed, and Hai Xiong*,A mitochondria-targeted fluorescent probe based on biocompatibleRBH-Ufor theenhanced responseofFe3+in living cells and quenching ofCu2+in vitro.Analytica Chimica Acta, 2023,1249, 340925.
13.Long Zhao, Farid Ahmed, Yating Zeng, Weiqing Xu, and Hai Xiong*,Recent Developments in G‑Quadruplex Binding Ligands and Specific Beacons on Smart Fluorescent Sensor for Targeting Metal Ions and Biological Analytes.ACS Sensors, 2022,7, 2833−2856.
12.Farid Ahmed, Shahzad Iqbal, and Hai Xiong*,Multifunctional Dual Emissive Fluorescent Probe Based on Europium-doped Carbon Dots (Eu-TCA/NCDs) for Highly Selective Detection of Chloramphenicol, Hg2+and Fe3+.Environmental Science-Nano, 2022, 9, 2624-2637.(Front Cover)
11. Long Zhao, Farid Ahmed, and Hai Xiong*,An excimer ‘ON –OFF’ switch based on telomeric G-quadruplex and rGO for trace thrombin detection.Chinese Chemical Letters, 2022,33, 4243–4247.
10.Jabrane Jouha, and Hai Xiong*, DNAzyme-Functionalized nanomaterials: Recent Preparation, Current Applications, and Future Challenges.Small, 2021, 17, 2105439.(Cover)
9.Farid Ahmed, Shahzad Iqbal, Long Zhao, and Hai Xiong*,“ON-OFF-ON” fluorescence switches based on N,S-doped carbon dots: Facile hydrothermal growth, selective detection of Hg2+, and as a reversive probe for guanine.Analytica Chimica Acta, 2021, 1183, 338977.
8. Shahzad Iqbal, Farid Ahmed, and Hai Xiong*, Responsive-DNA hydrogel based intelligent materials: Preparation and applications.Chemical Engineering Journal, 2021, 420, 130384.
7. Qiuyun Xiao, Xuan Zhao, and Hai Xiong*, Biocompatible and noncytotoxic nucleoside-based AIEgens sensor for lighting-up nucleic acids.Chinese Chemical Letters, 2021,32, 1687–1690. (Front Cover)
6. Xuan Zhao, Long Zhao, Qiuyun Xiao, and Hai Xiong*, Intermolecular hydrogen-bond interaction to promote thermoreversible 2'-deoxyuridine-based AIE-organogels.Chinese Chemical Letters, 2021, 32, 1363–1366.
5. Farid Ahmed, and Hai Xiong*, Recent developments in 1,2,3-triazole-based chemosensors.Dyes and Pigments, 2021, 185, 108905.
4. H. Xiong, N. Reynolds, C. Fan, M. Englert, D. Hoyer, S. Miller and D. Söll*, Dual Genetic Encoding of Acetyl-lysine and Non-deacetylatable Thioacetyl-lysine Mediated by Flexizyme.Angew. Chem. Int. Ed. 2016,55, 4083-4086.
3.C. Fan*, H. Xiong,N. Reynolds and D. Söll*, Rationally evolving tRNAPylfor efficient incorporation of noncanonical amino acids.Nucleic Acid Research. 2015,43(22):e156
2.G. Qing#, H. Xiong#(Co-first authors), F. Seela* and T. Sun*, Spatially Controlled DNA Nano-patterns by “Click” Chemistry Using Oligonucleotides with Different Anchoring Sites.J. Am. Chem. Soc., 2010,132, 15228-15232.
1. H. Xiong, F. Shi and Y. Deng*,Synthesis and application of supported cobalt catalyst for selective oxidation of cyclohexane and toluene.Chin. J. Catal., 2004,25(11), 887-891.
Book-Chapter
SPRINGER NATURE: Book entitled “Metal, Metal-Oxides and Metal Sulfides for Batteries, Fuel Cells, Solar Cells, Photocatalysis and Health Sensors” 2021,ISBN 978-3-030-63791-0 (eBook)
Chapter 8: Developing Trends in DNA Biosensor and Their Applications---Chandrasekar Selvaraj, Srinivas Bitta Thirumalavenkata and Hai Xiong*---
