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Huiping Hu

Deputy Director of Institute of Microbiology, Guangdong Academy of Sciences, Master Advisor

Hhp201#126.com

ORCID: https://orcid.org/0000-0002-4647-950X


Educational Background

1992.09-1996.06, Bachelor's degree in Bioengineering, South China University of Technology


Work Experience

1996.7 up to now, Institute of Microbiology, Guangdong Academy of Sciences


Research Field

Microbiology, Edible Fungi, Medicinal Fungi, and Fungal Resources


Representative Research projects

1. National Key Research and Development Project for the 14th Five Year Plan: Construction and Resource Exploration of a Large Database of Edible Microbiology Science, 2023YFF1104101, 2024-2027, Hosted and Under Research.

2. Provincial Rural Revitalization Strategy Special Fund Seed Industry Revitalization Project: Guangdong Edible Fungi (Shaoguan) Seed Industry Innovation Park, 2022-WJS-00-001, 2023-2024, hosted, under research.

3. Guangdong Provincial Science and Technology Project: Breeding and Demonstration Promotion of Excellent Varieties ofGanoderma lingzhiin Linzhi, 2016B02021008, 2016-2018, Hosted and Completed.

4. Guangdong Provincial Science and Technology Project: Investigation and Talent Cultivation of Edible and Medicinal Fungi Resources in Linzhi Prefecture, 2013B020315002, 2014-2016, Hosted and Completed.

5. Guangdong Provincial Science and Technology Project: Cultivation and Resource Investigation of Edible and Medicinal Fungi Talents in Linzhi, Tibet, 2012B020500006, 2012-2015, Hosted and Completed.

6. Science and Technology Project of Guangdong Province: Research on the Resources of Edible and Medicinal Fungi and Demonstration of Cultivation of Excellent Varieties in Linzhi, Tibet, 2011B020700001, 2011-2012, Hosted and Completed.

7. Guangdong Province Science and Technology Project: Domestication and Cultivation of Wild Ganoderma lucidum Varieties and Comparison of Anti tumor Functional Products, 2011B020303004, 2011-2013, Hosted and Completed.

8. 12th Five Year Science and Technology Support Program Project: Research and Demonstration of Precision Production Technology for Edible Fungi, 2013BAD16B05, 2013-2016, Mainly Participated in and Completed.

9. Foreign Cooperation Project of the Ministry of Science and Technology: Demonstration and Application of Key Technologies for High Quality and Efficient Large scale Production of Edible Fungi in Africa, 2009DFA30830, 2008-2010, Mainly Participated in and Completed.

10. National Natural Science Foundation of China: The chemical composition of ethanol extract of Tibet's new strain,Ganoderma leucocontextum, inhibiting the growth of breast cancer and its mechanism of action, 31700020, 2018-2020, Participated in and Completed.


Representative Awards

1. In 2010, the local standard "Flammulina velutipes" (DB44/T462-2008) in Guangdong Province won the third prize of Guangdong Province Standard Innovation Award (ranked 5th)

2. In 2013, "Key Technologies for Industrialized Production and Deep Processing of Edible and Medicinal Fungi" won the first prize of Guangdong Provincial Science and Technology Award (ranked 14th)

3. In 2018, "Artificial cultivation ofGanoderma leucocontextum" won the Excellent Product Award at the China International High tech Achievement Fair

4.In 2021, patent “Ganoderma leucocontextumstrain and its cultivation method and applications” won the Guangdong Patent Silver Award (ranked 1st)


Professional Affiliations

general Secretary of Guangdong Edible Fungi Association

Representative publications (selected from 81 papers)

(# Co-first author, * Corresponding author)

1. Huiping Hu, Yifan Zhang, Zhi Zhang, Manchao Shao, Qingping Wu, KETO Mshigeni, Xiaobing Yang. Bioactive Components in Cultivated Fruit Bodies of Three Wild Ganoderma Strains Collected from Tanzania[J]. Acta Edulis Fungi, 2011, 18(3):64-66.

2. Huiping Hu, Danzhen Ciren, Xiaobing Yang, Zhi Zhang, Manchao Shao, Zhenhui,Zhou, Lanying Ru. Edible and Officinal Wild Fungi Resources in Tibet Nyingchi Area[J]. Journal of Microbiology, 2013, (2):59-62.

3. Yaheng Shen, Ting Li, Huiping Hu, Weiping Xiong, Wenjuan Yan, Taihui Li.Ganoderma leucocontextum-an lmportantGanodermaSpecies from Southwestern China[J]. Acta Edulis Fungi, 2015, 22(4):49-52

4. Huiping Hu, Yuanchao Liu, Weipeng Mo, Longhua Huang, Yifan Zhang, Taihui Li, Rong Chen, Yizhen Xie. Isolation, Characterization and Anti-cancer Activity of TwoGanoderma leucocontextumStrains[J]. Acta Edulis Fungi, 2017, 24(1):50-54.

5. Zhi Zhang, Wuping Tan, Yuanchao Liu, Weipeng Mo, Longhua Huang, Zhiyong Huang, Dongmei Chen, Huiping Hu, Rongli Yu. lsolation, ldentification and Cultivation of a Wild-typeFlammulina fennae[J]. Acta Edulis Fungi, 2017, 24(1):45-49.

6. Qingping Wu, Huiping Hu, Yuanchao Liu, Xiaowei Liang.Ganoderma leucocontextum, Originated fromthe Snow-Capped Plateau[J]. Biotic Resources, 2020, 42(05):602.

7. Xiaoguang Chen, Yuanchao Liu, Xiaowei Liang, Yizhen Xie, Qingping Wu, Huiping Hu*.An Overview on Edible and Medicinal Mushroom Databases[J]. Acta Edulis Fungi, 2020, 27(03):115-126.

8. Xiaoxian Wu, Yuanchao Liu, Ao Wang, Lijun Zhuo, Huiping Hu*.lsolation,identification and its antibacterial activity of an endophytic fungus ofRussula griseocarnosa[J]. Biotic Resources, 2020, 42(05):585-592.

9. Na Du, Huiping Hu*, Yizhen Xie, Tianqiao Yong, Weipeng Mo, Xiaowei Liang, Lijun Zhuo.Research Progress onOudemansiella raphanipes[J]. Edible Fungi of China, 2020, 39(10):1-5,10.

10. Jun Niu, Ao Wang, Chuan Shi, Lijun Zhuo, Yizhen Xie, Wenzhi Li, Huiping Hu*.Advance Research on Hypoglycemic Effect of Edible Fungi in China[J]. Edible Fungi of China, 2020, 39(01):1-7,15.

11. Chuan Shi, Huiping Hu*, Weipeng Mo, Yuanchao Liu, Yizhen Xie. Cultivation and Antioxidant Activity ofOudemansiella crassifolia[J]. Acta Edulis Fungi, 2019, 26(4):78-83.

12. Yuanchao Liu, Xiaowei Liang, Weipeng Mo, Lijun Zhuo, Huiping Hu*, Longhua Huang, Yizhen Xie.Research Advances on Preservation of Edible Mushroom[J]. Edible Fungi of China, 2018, 37(5):1-6.

13. Longhua Huang, Wuping Tan, Yuanchao Liu, Zhiyong Huang, Yuanmao Zhong, Chuan Shi, Huiping Hu*.Molecular ldentification and Genetic Diversity Analysis of WildFlammulina sp.[J]. Edible Fungi of China, 2018, 37(4):52-56.

14. Longhua Huang, Feng He, Yuanchao Liu, Zhiyong Huang, Yuanmao Zhong, Chuan Shi, Huiping Hu*.A Rapid ldentification Method ofGanoderma leucocontextum[J]. Journal of Agricultural Biotechnology, 2017, (01):159-164.

15. Weipeng Mo, Yuanchao Liu, Huiping Hu*, Longhua Huang, Xiaowei Liang, Yizhen Xie. Preliminary Study on Biological Characteristics ofGanoderma leucocontextum[J]. Edible Fungi of China, 2017, 36(6):33-38.

16. Xiaowei Liang, Yuanchao Liu, Longhua Huang, Yizhen Xie, Feng He, Huiping Hu*. Advances in the Genus of Sanghuangporus Study[J]. Journal of Microbiology, 2017, 37(06):98-104.

17. Feng He, Wuping Tan, Longhua Huang, Yuanchao Liu, Huiping Hu*.Progress in Schizophyllan Research[J]. Acta Edulis Fungi, 2016, 23(2):88-93

18. Longhua Huang, Fengna Xia, Manchao Shao, Yifan Zhang, Duoyang Chen, Huiping Hu*.Identification ofHypsizigus marmoreusFruit Body with Different Origin Based on Molecular Markers[J]. Edible Fungi of China, 2014, 33(1):34-36.

19. Tai-hui Li, Hui-Ping Hu, Wang-Qiu Deng, Sheng-Hua Wu, Dong-Mei Wang, Tamdrin Tsering. Ganoderma leucocontextum, a new member of theG. lucidumcomplex from southwestern China[J]. Mycoence, 2015, 56(1):81-85.

20. Manjun Cai, Xiaowei Liang, Yuanchao Liu, Huiping Hu, Yizhen Xie, Shaodan Chen, Xiong Gao, Xiangmin Li, Chun Xiao, Diling Chen, Qingping Wu. Transcriptional Dynamics of Genes Purportedly Involved in the Control of Meiosis, Carbohydrate, and Secondary Metabolism during Sporulation inGanoderma lucidum[J]. Genes, 2021, 12(4).

21. HU Huiping, Y Liu, X Liang, LI Xiangmin, WU Qingping. Artificial Cultivation and Anti-tumor Activity of Ganoderma mbrekobenum[J]. Sains Malaysiana, 2021, 50(3):723-733.

22. Yuan chao Liu, Xiao cui Tang, Hui ping Hu#, Di ling Chen, Yi zhen Xie, Xiao wei Liang, Xiang min Li,Chun Xiao, Long hua Huang and Qing ping Wu.Genetic diversity and main functional composition of Lingzhi strains from main producing areas in China[J]. AMB Express, 2021, 11:119.

23. Yuanchao Liu, Huiping Hu#, Manjun Cai, Xiaowei Liang, Xiaoxian Wu, AoWang, Xiaoguang Chen, Xiangmin Li, Chun Xiao, Longhua Huang, YizhenXie, Qingping wu.Whole genome sequencing of an edible and medicinal mushroom,Russula griseocarnosa, and its association with mycorrhizal characteristics[J]. Gene, 2022, https://doi.org/10.1016/j.gene.2021.145996.

24. Yuanchao Liu, Longhua Huang, Huiping Hu#, Manjun Cai, Xiaowei Liang , XiangminLi, Zhi Zhang, Yizhen Xie, Chun Xiao, Shaodan Chen, Diling Chen, Tianqiao Yong,Honghui Pan, Xiong Gao, Qingping Wu. Whole-genome as sembly ofGanoderma leucocontextum(Ganodermataceae, Fungi) discovered from the Tibetan Plateau of China[J]. G3, 2021, https://doi.org/10.1093/g3journal/jkab337.

25.Huiyang Guo, Tong Wang, Huiping Hu*, Ming Jiang.Research Progress of Edible Fungus Enriched with Trace Elements[J].Edible Fungi of China, 2022, 41(04):1-8. DOI:10.13629/j.cnki.53-1054.2022.04.001.

26. Manjun Cai, Zengdong Tan, Xiaoxian Wu, Xiaowei Liang, Yuanchao Liu, Yizhen Xie, Xiangmin Li,Chun Xiao, Xiong Gao, Shaodan Chen, Huiping Hu* and Qingping Wu. Comparative transcriptome analysis of genes and metabolic pathways involved in sporulation inGanoderma lingzhi[J]. Genes Genomes Genetics, 2022, 12(3):jkab448.

27. Delong Feng, Huiping Hu#, Tianqiao Yong, Chun Xiao, Longhua Huang, Yizhen Xie, Qingping Wu.Induction of sexual fruiting-body formation by pairing the opposite mating-type isolates ofCordyceps militaris[J]. Mycosystema, 2023, 42(01):34452. DOI:10.13346/j.mycosystema.220357.

28. Huiyang Guo, Yuanchao Liu, Xiaoxian Wu, Manjun Cai, Ming Jiang, Huiping Hu*. Study on the inhibitory effect of fermentation extract of Microporus vernicipes on Candida albicans[J]. International microbiology: the official journal of the Spanish Society for Microbiology, 2023,https://doi.org/10.1007/s10123-023-00467-6.


Representative patents (selected from 50 patents)

1. A Cultivation Method ofOudemansiella raphanipes, ZL201210104685.5

2. A New Strain ofGanoderma tsugaeand Its Cultivation Method, ZL201310136820.9

3. A Method of Using Labels for Recording during the Process of Collecting Fungi, ZL201310512436.4

4. A Preparation Method ofAntrodia camphorate’s Stock Culture, ZL201310719336.9

5. Artificial Cultivation Method ofAmauroderma rudis, ZL201310737785.6

6. A Portable Detachable Box for Inoculation, ZL201410186096.5

7. A New Strain ofAuricularia auriculaand Its Artificial Cultivation Method, ZL201410186411.4

8. A New Fungal Strain ofLentinustuber-regiumand Its Cultivation Method and Applications, ZL201410809652.X

9 A Management System of Edible and Medicinal Fungi Database, 2015SR080808

10. A Artificial cultivation method for wildPanus neostrigosus, ZL201510075762.2

11. A Portable Mushroom Oven, ZL201520145383.1

12.Ganoderma leucocontextumStrain and Its Cultivation Method and Applications, ZL201610246676.8

13. The Application ofGanoderma leucocontextumExtract in Antiviral Drugs, ZL201610246680.4

14. A New Strain with High Yield of Polysaccharides and Its Cultivation Method and Applications, ZL201610316939.8

15. AFlammulina FennaStrain and Its Cultivation Method, ZL201610373181.1

16. A New Strain of0udemansiella crassifolia, and Its Cultivation Methodand and Applications, ZL201610658412.3

17. A Medium Simple Sorter, ZL201621385277.1

18. A Strain ofSchizophylla communeand Its Domestication Cultivation Method and Applications, ZL201611193054.X

19. A Strain ofXylariaceae sp.and Its Cultivation Method, ZL201710139813.2

20. A Strain of Mycorrhizal Fungi and Its Application in Anti-tumor Treatment, ZL201710771269.3

21. The Fruiting Bodies of A Mycorrhizal Fungal and Their Application in Anti-tumor Treatment, ZL201710771284.8

22. A New Strain ofIsaria tenuipesand Its Cultivation Methods and Uses, ZL201710848222.2

23. A New Strain ofGymnopilus luteofoliusand Its Cultivation Method and Uses, ZL201711006182.3

24. A Collection Device for Liquid-cultured Fungal Mycelium, ZL201721493789.4

25. An Application ofGanoderma leucocontextumpolysaccharides in The Preparation of Anti-tumor Drugs, ZL201811387888.3

26. The Edible and Medicinal Fungal Resources Database System of Guangdong Institute of Microbiology, 2019SR0059565

27. A New Strain ofHypholoma fasciculareand Its Artificial Cultivation Method and Applications, ZL201811525468.7

28. A New Strain ofLentinus squarrosulusand Its Domestication Cultivation Method and Applications,ZL201811583831.0

29. A New Strain ofPiptoporus soloniensisand Its Cultivation Method Based on Fungal Bran Substrate and Its Uses, ZL201910250401.5

30. A New Strain ofGanoderma mbrekobenumand Its Artificial Cultivation Method and Applications, ZL201910286040.X

31. A New Strain ofGanoderma enigmaticumand Its Artificial Cultivation Method and Applications, ZL201910286067.9

32. A Strain ofPycnoporus sanguineusand Its Artificial Cultivation Method and Uses, ZL201910879853.X

33. A New Strain ofPholiota sp.and Its Artificial Cultivation Method and Uses, ZL201911057539.X

34. A White Variety ofOudemansiella raphanipesand Its Artificial Cultivation Method, ZL201911167051.2

35. A New Strain ofIsaria cicadaeand Its Applications in Anti-tumor and Antibacterial, ZL202010929239.2

36. New Strain ofPanellus edulisand Its Artificial Cultivation Method, ZL202011792669.9

37. A Movable and Mortable Mycelium Growth Rate Measurement Box, ZL202022292445.5

38. A New Strain ofOudemansiella raphanipesand Its Artificial Cultivation Method and Uses, ZL22010554107.6

39. A New Endophytic Fungus ofRussula griseocarnosaand Its Extracts’ Application in Antibacterial, ZL202010410225. X

40. A New Strain ofMicroporus vernicipesand Its Fermentation Method and Application in Antibacterial, ZL202011145282.6

41. Molecular Markers, Specific Primers, and Identification Method for The High-quality Strain I140033 ofGanoderma leucocontextum, ZL202110460314. X



Curriculum Vitae

Huiping Hu, female, senior engineer, master advisor, general Secretary of Guangdong Edible Fungi Association. Ms. Hu is mainly engaged in the research of edible and medicinal fungi’s resources collection, breeding, cultivation, fermentation application, etc. She constructed the largest germplasm resource bank and database of wild edible and medicinal fungi in China, with a total of over 26,000 specimens, over 9,000 strains, and over 11,000 pieces of genetic data of molecular identification. Based on the database, the genome ofGanoderma leucocontextum, a new species ofGanoderma sp.,Flammulina Fenna, a new record species ofFlammulinasp.in China, andRussula griseocarnosa, an important mycorrhizal fungus, have been analyzed for the first time, and the sporulation genes ofGanoderma lucidumwere identified by transcriptome analysis. The regularity of occurrence and distribution of wild edible and medicinal fungi, as well as the relationship between species and geography and climate have been initially revealed by resequencing andcombining withthe cultivation characteristics ofGanoderma lucidumandCordyceps militariscollected nationwide. Based on the germplasm resource bank, 616 edible and medicinal fungi were successfully domesticated, a batch of high-quality strains, such asGanoderma leucocontextum,Flammulina FennaandOudemansiella raphanipes, were promoted and applied, and a batch of rare strains with high polysaccharide content and/or high triterpenoid content were isolated and screened. Among them, the publication and promotion ofGanoderma leucocontextum, a new species ofGanodermasp., have made innovative contributions to the cultivation ofGanoderma sp.from scratch to industrialization in Linzhi and even Tibet. She has undertaken more than 10 national, provincial and ministerial scientific research projects, including national key research and development projects. She has 81 publications, listed as the first or corresponding author on 31. She is also the patent holder of 50 national inventions of China patent, listed as the first inventor on 24. One of the patents, “Ganoderma leucocontextumstrain and its cultivation method and applications” won the silver Award of the 8th Guangdong Provincial Patent Award. She identified a new species ofGanoderma sp.,Ganoderma leucocontextum, and won the first prize of Guangdong Provincial Science and Technology Award and the third prize of Guangdong Provincial Standard Innovation contribution.



Address: Institute for Advanced Study

Shenzhen University

Nanshan District

Shenzhen, Guangdong

China 518060

Tel: +86-755-2649-2572

CopyRight@Institute for Advanced Study,Shenzhen University.