Ph.D., Microbiology (2012), Shanghai Jiao Tong University

M.S., Biochemistry and Molecular Biology (2007), Hainan University

B.S., Food Science and Engineering (2004), Hainan University

02/2019－present, Professor Institute of Microbiology, Guangdong Academy of Sciences

02/2018－01/2019, Postdoctoral Research Fellow, Luxembourg University

02/2012. 02－12/2018, Postdoctoral Research Fellow, Brown University

R&D of synthetic biosensing systems for food safety testing, National Key R&D Program (2021YFA0910200), 2021-2026, PI.

Targeted breeding of important healthy microbial strains and research and development of functional products, Guangdong Province Key Areas Research and Development Programs (2022B1111070006), 2022-2025, PI.

Enzymatic mechanisms of chiral selection and control of the core domain of biosynthetic polyketide synthases,Guangdong Academy of Sciences 100 Talents Program (2020GDASYL-20200102003), 2020-2024, PI.

Enzymatic mechanisms of dimethyltransferases and dehydrases in polyketide synthases,NSFC (21977020), 2020-2023, PI.

Prevention and control of foodborne pathogens based on metabolic control and engineering of probiotic microorganisms, Organization Department of the CPC Central Committee, 2020-2022, PI.

Study on the interaction mechanism between active components of edible and medicinal fungi and intestinal microbiota, The Pearl River Talent Plan of Guangdong Province - Top Young People (2019QN01N107), 2020-2024, PI.

02/2023, Distinguished expert of global wisdom program, China Association for Science and Technology

12/2022, Distinguished expert of global wisdom program, Guangdong Province Association for Science and Technology

12/2022, "Tianfu Scholar" Distinguished Expert, Sichuan Provincial Department of Human Resources and Social Security

02/2020, Thousand Talents Plan (Young Professionals)

1.Xinqiang Xie, Chaitan Khosla, David E Cane*. Elucidation of the Stereospecificity of C-Methyltransferases fromtrans-AT Polyketide Synthases.J Am Chem Soc.2017; 139(17): 6102-6105.

2.Xinqiang Xie,Ashish Garg, Chaitan Khosla, David E Cane*. Mechanism and Stereochemistry of Polyketide Chain Elongation and Methyl Group Epimerization in Polyether Biosynthesis.J Am Chem Soc. 2017; 139(8):3283-3292.

3.Xinqiang Xie, Ashish Garg, Chaitan Khosla, David E Cane*. Elucidation of the Cryptic Methyl Group Epimerase Activity of Dehydratase Domains from Modular Polyketide Synthases Using a Tandem Modules Epimerase Assay.J Am Chem Soc. 2017; 139(28):9507-9510.

4.Xinqiang Xie#, Jingdan Liang#, Tianning Pu, Fei Xu, Fen Yao, Yan Yang, Yi-Lei Zhao, Delin You, Xiufen Zhou, Zixin Deng*, Zhijun Wang*. Phosphorothioate DNA as an antioxidant in bacteria.Nucleic Acids Res. 2012; 40(18):9115-24.

5.Ashish Garg#,Xinqiang Xie#, Adrian Keatinge-Clay, Chaitan Khosla, David E Cane*. Elucidation of the cryptic epimerase activity of redox-inactive ketoreductase domains from modular polyketide synthases by tandem equilibrium isotope exchange.J Am Chem Soc. 2014; 136(29):10190-3.

6.Lei Wu #,Xinqiang Xie#, Ying Li #, Tingting Liang, Haojie Zhong, Lingshuang Yang, Yu Xi, Jumei Zhang, Yu Ding*, Qingping Wu*. Gut microbiota as an antioxidant system in centenarians associated with high antioxidant activities of gut-resident Lactobacillus.NPJ Biofilms Microbiomes.2022; 8(1):102.

7.Tingting Liang #,Xinqiang Xie#, Lei Wu#, Longyan Li, Lingshuang Yang, Tong Jiang, Mingzhu Du, Moutong Chen, Liang Xue, Jumei Zhang, Yu Ding*, Qingping Wu*. Metabolism of resistant starch RS3 administered in combination withLactiplantibacillus plantarumstrain 84-3 by human gut microbiota in simulated fermentation experiments in vitro and in a rat model.Food Chem.2023; 411:135412.

8.Longyan Li, Tingting Liang, Tong Jiang, Ying Li, Lingshuang Yang, Lei Wu, Juan Yang, Yu Ding, Juan Wang, Moutong Chen, Jumei Zhang,Xinqiang Xie*, Qingping Wu*. Gut microbiota: Candidates for a novel strategy for ameliorating sleep disorders.Crit Rev Food Sci Nutr.2023; pp: 1-17.

9.Hao-Jie Zhong # , Si-Qi Wang # , Ruo-Xin Zhang # , Yu-Pei Zhuang, Longyan Li, Shuo-Zhao Yi, Ying Li, Lei Wu, Yu Ding, Jumei Zhang,Xinqiang Xie*, Xing-Xiang He*, Qingping Wu*. Supplementation with high-GABA-producingLactobacillus plantarumL5 ameliorates essential tremor triggered by decreased gut bacteria-derived GABA.Transl Neurodegener.2023; 12(1):58.

10.Hui Zhao, Yue Su, Qihui Gu, Jumei Zhang,Xinqiang Xie*, Qingping Wu*.Paenibacillus soyaesp. nov., isolated from the rhizosphere of soya bean.Int J Syst Evol Microbiol.2023; 73(4).