Education:
9/2010~7/2015 Graduate student (Ph. D. degree) Polymer Chemistry Department of Chemistry Tsinghua University
9/2006~7/2010 Undergraduate student (B. S. degree) Pilot Class in Natural Science (Chemistry and Biotechnology) Jilin University, P. R. China
Research Experience:
6/2026~ Principle Investigator, Professor The Institute for Advanced Study, Shenzhen University, Shenzhen, 518060, Guangdong, China
10/2018~6/2026 Principle Investigator, Professor CAS Key Laboratory of Colloid, Interface and Chemical Thermodynamics Institute of Chemistry, Chinese Academy of Sciences, P. R. China
8/2015~10/2018 Postdoc Research Dana-Farber Cancer Institute, Harvard Medical School Harvard, USA
Research Interests:
1. Frame Guided Assembly to prepare amphiphilic assemblies with controllable shapes and sizes at nanometer scale;
2. Preparation of DNA Supramolecular Hydrogels and their application;
3. Investigate structure and dynamics of Bio-Macromolecules with Cryo-EM;
4. Develop novel strategy to prepare nano-scale lipid membranes
Publications:
1. Chuangyuan Zhao, Wenhao Shi, Xiaowei Li, Yang Ying, Yu Jin, Guizhi Dong, Dongsheng Liu, Yuanchen Dong.* Site-Specific and Regioselective Modification of Human Epidermal Growth Factor Receptor 2 via Site-Sculpted DNA Nanorefiners. Angew. Chem. Int. Ed. 2026, 65 (5), e18641.
2. Chenyou Zhu, Yin Xu, Ziyang Hao, Yuan Zhuang, Rui Xu, Yufan Pan, Jiezhong Shi, Yujie Li, Yifan Jiang, Tianran Wang, Yuhe R. Yang, Huajie Liu, Dali Han, Yuanchen Dong,* Chuan He,* Dongsheng Liu.* Long Single-Stranded DNA with Site-Specific Modifications to Enable Single-Base-Resolution Epigenetics. Angew. Chem. Int. Ed. 2026, 65 (3), e13078.
3. Yue Li, Xue Li,* Miaomiao Qiu, Zhaowei Zhang, Lianqiang Dong, Zhengyang Wei, Lingwei Meng, Yuanjing Zheng, Yang Wang, Yuanlin Liu, Dongsheng Liu, Shaoxia Pan,* Yi Zhang,* Yuanchen Dong.* DNA Supramolecular Hydrogel Alters Exosomal microRNA Atlas and Paracrine Secretory Profile of MSCs to Promote Bone Remodeling and Ameliorate Osteoradionecrosis of the Jaw. Adv. Mater. 2026, n/a (n/a), e23658.
4. Miaomiao Qiu, Jing Wang, Xinchang Pang, Dongsheng Liu,* Yuanchen Dong.* Preparation strategies and biomedical applications of DNA hydrogels. Chem. Sci. 2026, 17 (8), 3875-3893.
5. Yufan Pan, Xin Li, Liangzhi Luo, Rui Xu, Chenyou Zhu, Sijie He, Jun Wu, Ruofan Chen, Yifan Jiang, Yuanchen Dong, Ziyang Hao,* Dongsheng Liu.* Circular Single-Stranded DNA for Simultaneous Suppression of Multiple miRNAs. CCS Chem. 2026, 8 (1), 441-452.
6. Guizhi Dong, Jiafang Piao, Wei Yuan, Chuangyuan Zhao, Xiao Li, Rui Xu, Dongsheng Liu, Yuanchen Dong.* Construct Open Lipid Nano-Membranes with Controllable Lateral Behavior. J. Am. Chem. Soc. 2025, 147 (43), 39359-39366.
7. Guizhi Dong, Jiafang Piao, Chao Wang, Chuangyuan Zhao, Shuwen Zhang, Wei Yuan, Shitao Zou, Yujie Li, Youdong Mao, Dongsheng Liu, Yuanchen Dong.* DNA-Lipid Nano-Canvas for Investigating Membrane Protein Structure. CCS Chem. 2025, 7 (10), 3076-3086.
8. Ruofan Chen, Yuan Zhuang, Li Zhang, Yuanyuan Wu, Liangzhi Luo, Yufan Pan, Yujie Li, Chenyou Zhu, Rui Xu, Yifan Jiang, Ziyang Hao, Baolei Tian, Liang Zhang, Yuanchen Dong,* Dongsheng Liu.* A Computationally Optimized Ribonucleic Acid Circularization Strategy without Byproducts. J. Am. Chem. Soc. 2025, 147 (36), 32932-32940.
9. Yufan Pan, Chenyou Zhu, Yuan Zhuang, Xin Li, Rui Xu, Yifan Jiang, Yuanchen Dong,* Chuan He, Dongsheng Liu,* Xi Zhang. Synthesis of Precisely Modified Ribonucleic Acid to Reveal the Site-Specific Effect of Modification on Message Ribonucleic Acid Translation. J. Am. Chem. Soc. 2025, 147 (43), 39751-39760.
10. Yufan Pan, Xin Li, Chenyou Zhu, Mingyan Wang, Yuanyuan Wu, Rui Xu, Jun Wu, Ruofan Chen, Yifan Jiang, Baolei Tian, Yuanchen Dong,* Dongsheng Liu.* Programmable Single-Stranded Circular Antisense Oligonucleotides for Multitarget Gene Therapy. JACS Au 2025, 5 (7), 3555-3564.
11. Chuangyuan Zhao, Xinran Jiang, Miao Wang, Songbai Gui,* Xin Yan,* Yuanchen Dong,* Dongsheng Liu.* Constructing protein-functionalized DNA origami nanodevices for biological applications. Nanoscale 2025, 17(1), 142-157.
12. Ziwei Shi, Jiarui Li, Miaomiao Qiu, Lianqiang Dong, Dongsheng Liu, Lijin Xu, Yuanchen Dong. In Situ Stiffness Tunable DNA Hydrogels Based on Ring-Opening Polymerization. Small Methods 2025, 9 (12), e01478.
13. Jiarui Li, Ziwei Shi, Xiuji Du, Guizhi Dong, Yufan Pan, Ruofan Chen, Miaomiao Qiu, Yun Xu, Lijin Xu, Dongsheng Liu, Yuanchen Dong. Purifying Nucleic Acids through Redox-Responsive Polyacrylamide Gel Electrophoresis with Enhanced Recovery. ACS Appl. Polym. Mater. 2025, 7 (22), 15483-15492.
14. Yihui Zhao, Yusen Jie, Youcai Xue, Ziwei Shi, Yuanchen Dong, Murugappan Muthukumar, Di Jia.* Universal law of hierarchical dynamics in gels arising from confluence of local physically dynamic bonds. Nat. Commun. 2025, 16 (1), 3247.
15. Junbo Wang, Yufan Pan, Yixiao Liu, Bo Huang, Ge Jin, Lejin Zhang, Feng Zhou, Xiaoyu Chang, Yucen Huang, Liming Yan, Yuanchen Dong, Zihe Rao, Dongsheng Liu,* Zhiyong Lou.* Structural Basis and Rational Design of Nucleotide Analogue Inhibitor Evading the SARS-CoV-2 Proofreading Enzyme. J. Am. Chem. Soc. 2025, 147 (25), 21896-21906.
16. Mingchen Xiong, Xinling Yang, Ziwei Shi, Jiangbing Xiang, Huanhuan Gao, Shuaifei Ji, Yingying Li, Wei Pi, Huating Chen, Hongliang Zhang, Mengyang Wang, Yan Li, Yiyue Hong, Dongsheng Liu,* Xiaobing Fu,* Yuanchen Dong,* Xiaoyan Sun.* Programmable Artificial Skins Accomplish Antiscar Healing with Multiple Appendage Regeneration. Adv. Mater. 2024, 36(50), 2407322.
17. Yujie Li, Ruofan Chen, Bini Zhou, Yuanchen Dong,* Dongsheng Liu.* Rational Design of DNA Hydrogels Based on Molecular Dynamics of Polymers. Adv. Mater. 2024, 36(7), 2307129.
18. Ziwei Shi, Yujie Li, Xiuji Du, Dongsheng Liu, Yuanchen Dong.* Constructing Stiffness Tunable DNA Hydrogels Based on DNA Modules with Adjustable Rigidity. Nano Lett. 2024, 24(28), 8634-8641.
19. Xiangxiang Guan, Chenyou Zhu, Yuanchen Dong,* Dongsheng Liu,* Chengde Mao.* Multiple-unit interlocking enhances the single-stranded tiles assembly of DNA nanostructures. Nanoscale 2024, 16(42), 19642-19648.
20. Zongze Duan, Guizhi Dong, Hai Yang, Zhengwei Yan, Simin Liu, Yuanchen Dong,* Zhiyong Zhao.* Supramolecular DNA Nanogels through Host–Guest Interaction for Targeted Drug Delivery. J. Mater. Chem. B 2024, 12(25), 6137-6145.
21. Na Zhang, Lianqiang Dong, Yu Wang,* Xiaoyang Wang, Yixing Wen, Xueguang Lu, Yuanchen Dong,* Wei You.* Elucidating the backbone degradation mechanism of poly(7-oxa-2,3-diazanorbornene). Chem. Commun. 2024, 60(93), 13714-13717.
22. Wei Yuan, Guizhi Dong, Hui Ning, Xiangxiang Guan, Jiafeng Cheng, Ziwei Shi, Xiuji Du, Siwen Meng, Dongsheng Liu, Yuanchen Dong.* Applying dynamic light scattering to investigate the self-assembly process of DNA nanostructures. Chin. Chem. Lett. 2024, 35(3), 108384.
23. Bo Yang*, Ting Cui, Liang Guo, Lianqiang Dong, Jun Wu, Yongzheng Xing,* Yun Xu, Jian Chen, Yufei Wang, Zhonghui Cui, Yuanchen Dong.* Advanced Smart Biomaterials for Regenerative Medicine and Drug Delivery Based on Phosphoramidite Chemistry: From Oligonucleotides to Precision Polymers. Biomacromolecules 2024, 25(5), 2701-2714.
24. Xiuji Du, Yongzheng Xing, Yujie Li, Muqing Cao, Jun Wu, Guizhi Dong, Ziwei Shi, Xunan Wei, Miaomiao Qiu, Junjie Gao, Yun Xu, Huaping Xu, Dongsheng Liu, Yuanchen Dong.* Gradually Self-Strengthen DNA Supramolecular Hydrogels. Macromol. Rapid Comm. 2024, 45(16), 2400177.
25. Yujie Li, Wei Yuan, Xiancheng Tian, Chenyou Zhu, Xin Li, Ruofan Chen, Ziyang Hao, Yuanchen Dong,* Dongsheng Liu.* A facile method to prepare non-cationic mRNA lipid-nanoparticles based on frame guided assembly strategy. Nano Today 2023, 52, 101991.
26. Xu-nan Wei, Yujie Li, Xingdi Cheng, Yixing Wen, Wei Yuan, Ruofan Chen, Siwen Meng, Xueguang Lu, Zhiyong Yu,* Lijin Xu,* Dongsheng Liu, Yuanchen Dong.* Increase Nebulization Stability of Lipid Nanoparticles by Integrating a DNA Supramolecular Hydrogel. ACS. Macro. Lett. 2023, 6, 745-750.
27. Ruofan Chen, Yujie Li, Yu Jin, Yawei Sun, Zhiyong Zhao, Yun Xu, JiangFei Xu, Yuanchen Dong,* Dongsheng Liu.* Reinforcing supramolecular hyaluronan hydrogels via kinetically interlocking multiple-units strategy. Carbohydr. Polym. 2023, 310, 120703.
28. Wei Yuan, Jiafeng Cheng, Chenyou Zhu, Guizhi Dong, Xiaoping Zhao, Siwen Meng, Dongsheng Liu, Yuanchen Dong.* Preparing liposomes through frame guided assembly with high-loading functional nucleic acids. Nanoscale 2023, 15(23), 9946-9953.
29. Yuqiao Ding, Yujie Li, Bo Yang, Yufan Pan, Jiafeng Cheng, Siwen Meng, Dongsheng Liu,* Lijin Xu,* Yuanchen Dong.* Preparation of Photo-responsive DNA Supramolecular Hydrogels and Their Application as UV Radiometers. Chem. Res. Chinese Universities 2023, 39(1), 115-120.
30. Jiafeng Cheng, Wei Yuan, Yuqiao Ding, Xu-nan Wei, Zhiyong Yu,* Lijin Xu,* Yuanchen Dong.* Construction and Application of Size-controllable Spherical DNA Nanoparticles. Acta. Polym. Sin. 2023, 54(3), 336-345.
31. Shuailong Zhou, Jianhan Ye, Xiaohuan Zhao, Zihao Zhou, Yuanchen Dong, Qian Shi, Nannan Liu,* Fen Wu.* A DNA-Schiff base functional nanopore sensing platform for the highly sensitive detection of Al3+ and Zn2+ ions. Dalton Trans. 2023, 52(6), 1524-1532.
32. Meiqing Yang, Yuanchen Dong,* Chuang Li.* Light-Dissipative and Reprogrammable DNA Hydrogels Enabled by Merocyanine Photoacids. Chemistry of Materials, 2023, 35(23), 9978-9987.
33. Yufan Pan, Yuqiao Ding, Yuanchen Dong,* Dongsheng Liu.* Construction, Functionalization and Biomedical Application of DNA Supramolecular Hydrogels. Acta Polym Sin, 2023, 54(7), 1012-1027.
34. Bini Zhou, Bo Yang, Qian Liu, Lu Jin, Yu Shao, Taoyang Yuan, Ya-nan Zhang, Chao Wang, Ziwei Shi, Xin Li, Yufan Pan, Ning Qiao, Jiangfei Xu, Yuhe Renee Yang,* Yuanchen Dong, Lijin Xu, Songbai Gui,* Dongsheng Liu.* Effects of Univariate Stiffness and Degradation of DNA Hydrogels on the Transcriptomics of Neural Progenitor Cells. J. Am. Chem. Soc. 2023, 145(16), 8954-8964.
35. Jianhan Ye, Juanjuan Zheng, Xin Lu, Fen Wu,* Nannan Liu,* Yuanchen Dong, Qian Shi, Lijin Xu,* Dongsheng Liu. Single-Molecular Poly(propylene oxide) (PPO) Nucleus-Guided Assembly for Hydrophobicity-Dependent Molecular Transport in the Nanopore. Langmuir 2023, 39(12), 4537-4543.
36. Jianhan Ye, Xin Lu, Xiaohuan Zhao, Fen Wu,* Yuanchen Dong, Qian Shi, Lijin Xu.* DNA-decorated multilamellar cholesterol assemblies for nucleic acid detection in the micrometer-scale solid-state nanopore. Polymer 2023, 267, 125676.
37. Jiangming Wang, Yuanchen Dong, Huajie Liu,* Dongsheng Liu.* Nucleic Acid-Backboned Chimeric Polymers with Designable Physics and Chemistry. Chinese J. Chem. 2023, 41(8), 951-957.
38. Jiezhong Shi,* Ben Zhang, Tianyi Zheng, Tong Zhou, Min Guo, Ying Wang, Yuanchen Dong.* DNA Materials Assembled from One DNA Strand. Int. J. of Mol. Sci. 2023, 24(9), 8177.
39. Yanan Zhang, Ximei Hou, Jiafang Piao, Wei Yuan, Bini Zhou, Xiaoping Zhao, Ziyang Hao,* Yuan Zhuang,* Lijin Xu,* Yuanchen Dong,* Dongsheng Liu. Delivery and controllable release of anti-sense DNA based on frame-guided assembly strategy. European Polymer Journal 2022, 173, 111187.
40. Wei Yuan, Yuanchen Dong.* Recent Advancements in Frame-guided Assembly. Acta. Polym. Sin. 2022, 53(10), 1204-1216.
41. Jianhan Ye, Fen Wu,* Yuanchen Dong, Lijin Xu,* Dongsheng Liu.* Synthesis and Application of DNA-Organic Small Molecule Complex. Acta. Polym. Sin. 2022, 53(12), 1421-1429.
42. Jianhan Ye, Yulu Cao, Xin Lu, Fen Wu, Nannan Liu, Yuanchen Dong, Qian Shi.* Self-assembly of DNA-organic hybrid amphiphiles by frame-guided assembly strategies. Giant 2022, 11, 100113.
43. Bo Yang, Bini Zhou, Cuifeng Li, Xiaowei Li, Ziwei Shi, Yuxin Li, Chenyou Zhu, Xin Li, Yi Hua, Yufan Pan, Jian He, Tianyang Cao, Yawei Sun, Wanli Liu, Min Ge, Yuhe Renee Yang, Yuanchen Dong,* Dongsheng Liu.* A Biostable l-DNA Hydrogel with Improved Stability for Biomedical Applications. Angew. Chem. Int. Ed. 2022, 61(30), e202202520.
44. Tiantian Wu, Yuanwei Cao, Qing Liu, Xiaohui Wu, Yingxu Shang, Jiafang Piao, Yujie Li, Yuanchen Dong, Dongsheng Liu, Haoyi Wang,* Jianbing Liu,* Baoquan Ding.* Genetically Encoded Double-Stranded DNA-Based Nanostructure Folded by a Covalently Bivalent CRISPR/dCas System. J. Am. Chem. Soc. 2022, 144(14), 6575-6582.
45. Jiafang Piao, Chuangyuan Zhao, Yuanchen Dong.* DNA nanostructure-assisted nanodiscs provide a toolbox to investigate membrane proteins. Cell. Rep. Phys. Sci. 2022, 3(6), 100897.
46. Yufan Pan, Bo Yang, Rui Xu, Xin Li, Yuanchen Dong,* Dongsheng Liu.* Rigidity-dependent formation process of DNA supramolecular hydrogels. NPG Asia Materials 2022, 14(1), 92.
47. Yujie Li, Yuqiao Ding, Bo Yang, Tianyang Cao, Jiangfei Xu, Yuanchen Dong, Quan Chen, Lijin Xu, Dongsheng Liu.* Reinforcing DNA Supramolecular Hydrogel with Polymeric Multiple-Unit Linker. CCS Chemistry 2022, 5(5), 434-444.
48. Yu Jin, Yujie Li, Sijia Song, Yuqiao Ding, Yuanchen Dong, Yao Lu,* Dongsheng Liu,* Chun Zhang. DNA Supramolecular Hydrogel as a Biocompatible Artificial Vitreous Substitute. Adv. Mater. Interfaces 2022, 9(5), 2101321.
49. Yuanchen Dong, Yang Yang, Chenxiang Lin,* Dongsheng Liu.* Frame-Guided Assembly of Amphiphiles. Acc. Chem. Res. 2022, 55(14), 1938-1948.
50. Xiaobin Dai, Zhichao Zhu, Yujie Li, Bo Yang, JiangFei Xu, Yuanchen Dong,* Xin Zhou, Litang Yan,* Dongsheng Liu.* “Shutter” Effects Enhance Protein Diffusion in Dynamic and Rigid Molecular Networks. J. Am. Chem. Soc. 2022, 144(41), 19017-19025.
51. Zhiyong Zhao,* Yuanchen Dong,* Zongze Duan, Dou Jin, Wei Yuan, Dongsheng Liu.* DNA-organic molecular amphiphiles: Synthesis, self-assembly, and hierarchical aggregates. Aggregate 2021, 2(4), e95.
52. Taoyang Yuan, Yu Shao, Xu Zhou, Qian Liu, Zhichao Zhu, Bini Zhou, Yuanchen Dong, Nicholas Stephanopoulos, Songba Gui,* Hao Yan,* Dongsheng Liu.* Highly Permeable DNA Supramolecular Hydrogel Promotes Neurogenesis and Functional Recovery after Completely Transected Spinal Cord Injury. Adv. Mater. 2021, 33(35), 2102428.
53. Bo Yang, Zhihan Zhao, Yufan Pan, Jiayin Xie, Bini Zhou, Yujie Li, Yuanchen Dong, Dongsheng Liu.* Shear-Thinning and Designable Responsive Supramolecular DNA Hydrogels Based on Chemically Branched DNA. ACS. Appl. Mater. Inter. 2021, 13(41), 48414-48422.
54. Bo Yang, Limei Sun, Yufan Pan, Yuanchen Dong, Yawei Sun,* Dongsheng Liu.* Photo-responsive DNA Hydrogel Based on Photoactive Thymine Phosphoramidite Monomer. Acta. Polym. Sin. 2021, 52(8), 996-1005.
55. Xin Yan, Bo Yang, Yourong Chen, Yifan Song, Jing Ye, Yufan Pan, Bini Zhou, Yuqing Wang, Fengbiao Mao, Yuanchen Dong, Dongsheng Liu,* Jiakuo Yu.* Anti-Friction MSCs Delivery System Improves the Therapy for Severe Osteoarthritis. Adv. Mater. 2021, 33(52).
56. Wei Yuan, Jiafang Piao, Yuanchen Dong.* Advancements in the preparation methods of artificial cell membranes with lipids. Mater. Chem. Front. 2021, 5 (14), 5257-5297.
57. Jiafang Piao, Wei Yuan, Yuanchen Dong.* Recent Progress of DNA Nanostructures on Amphiphilic Membranes. Macromol. Biosci. 2021, 21 (5), 2000440.
58. Bini Zhou, Yuanchen Dong, Dongsheng Liu.* Recent Progress in DNA Motor-Based Functional Systems. ACS Appl. Bio. Mater. 2021, 4 (3), 2251-2261.
59. Jiezhong Shi, Chenyou Zhu, Qian Li, Yujie Li, Liangxiao Chen, Bo Yang, Jiangfei Xu, Yuanchen Dong, Chengde Mao, Dongsheng Liu.* Kinetically Interlocking Multiple-Units Polymerization of DNA Double Crossover and Its Application in Hydrogel Formation. Macromol. Rapid Comm. 2021, 42, 2100182.
60. Chao Wang, Jiafang Piao, Yujie Li, Xiancheng Tian, Yuanchen Dong,* Dongsheng Liu.* Construction of Liposomes Mimicking Cell Membrane Structure through Frame-Guided Assembly. Angew. Chem. Int. Ed. 2020, 59, 15176–15180.
61. Chao Wang, Yiyang Zhang, Yu Shao, Xiancheng Tian, Jiafang Piao, Yuanchen Dong,* Dongsheng Liu.* pH-responsive Frame-Guided Assembly with hydrophobicity controllable peptide as leading hydrophobic groups. Giant 2020, 1, 100006.
62. Yawei Sun,#* Bo Yang,# Yi Hua, Yuanchen Dong, Jianhan Ye, Jiqian Wang, Lijin Xu, Dongsheng Liu.* Construction and Characterization of a Mirror-Image l-DNA i-Motif. Chembiochem 2020, 21 (1-2), 94-97.
63. Jiezhong Shi, Ziwei Shi, Yuanchen Dong, Fen Wu,* Dongsheng Liu.* Responsive DNA-Based Supramolecular Hydrogels. Acs Appl Bio Mater 2020, 3 (5), 2827-2837.
64. Yujie Li,# Chenyou Zhu,# Yuanchen Dong, Dongsheng Liu.* Supramolecular hydrogels: Mechanical strengthening with dynamics. Polymer 2020, 210, 122993.
65. Yujie Li, Jie Chen, Yuanchen Dong, Huajie Liu,* Dongsheng Liu.* Construction of pH-Triggered DNA Hydrogels Based on Hybridization Chain Reactions. Chem. Res. Chinese Universities 2020, 36 (2), 243-246.
66. Tianyang Cao, Haoyang Jia, Yuanchen Dong, Songbai Gui,* Dongsheng Liu.* In Situ Formation of Covalent Second Network in a DNA Supramolecular Hydrogel and Its Application for 3D Cell Imaging. ACS Appl. Mater. Inter. 2020, 12 (4), 4185-4192.
67. Yuanchen Dong,# Shuwen Zhang,# Zhaolong Wu, Xuemei Li, Wei Li Wang, Yanan Zhu, Svetla Stoilova-McPhie, Ying Lu, Daniel Finley, Youdong Mao.* Cryo-EM Structures and Dynamics of Substrate-Engaged Human 26S Proteasome. Nature 2019, 565 (7737), 49-55.
68. Yiyang Zhang,# Chao Wang,# Yuanchen Dong,* Dianming Wang, Tianyang Cao, Shuo Wang, Dongsheng Liu.* Fold 2D Woven DNA Origami to Origami+ Structures. Adv. Funct. Mater. 2019, 29 (22), 1809097.
69. Shuo Wang, Yiyang Zhang, Yuanchen Dong,* Dongsheng Liu.* Redox Triggered Disassembly of Frame-Guided Assemblies. Polymer 2019, 175, 146-151.
70. Yuanchen Dong,* Youdong Mao.* DNA Origami as Scaffolds for Self-Assembly of Lipids and Proteins. ChemBioChem 2019, 20 (19), 2422-2431.
71. Rui Fang, Robin Chen, Jason Hon, Jiayi Wu, Yuanchen Dong, Yanan Zhu, Youdong Mao, Qi Ouyang, Daniel Finley, Ying Lu.* The conformational landscape of the human 26S proteasome by Cryo-EM structural analysis. J. Biomol. Struct. Dyn. 2019, 37 (S1), 6.
72. Haoyang Jia, Jiezhong Shi, Weibin Ren, Jiang Zhao, Yuanchen Dong, Dongsheng Liu.* Controllable supramolecular “ring opening” polymerization based on DNA duplex. Polymer 2019, 171, 121-126.
73. Jiezhong Shi,# Haoyang Jia,# Hao Chen, Xi Wang, Jiang-Fei Xu, Weibin Ren, Jiang Zhao, Xin Zhou, Yuanchen Dong, Dongsheng Liu.* Concentration Insensitive Supramolecular Polymerization Enabled by Kinetically Interlocking Multiple-Units Strategy. CCS Chem. 2019, 1 (3), 296-303.
74. Hengyuan Liu,# Tianyang Cao,# Yun Xu, Yuanchen Dong, Dongsheng Liu.* Tuning the Mechanical Properties of a DNA Hydrogel in Three Phases Based on ATP Aptamer. Int. J. Mol. Sci. 2018, 19 (6), 1633.
75. Yuanchen Dong, Shuobing Chen, Shijian Zhang, Joseph Sodroski, Zhongqiang Yang, Dongsheng Liu, Youdong Mao.* Folding DNA into a Lipid-Conjugated Nanobarrel for Controlled Reconstitution of Membrane Proteins. Angew. Chem. Int. Ed. 2018, 57 (8), 2072-2076.
76. Bo Bian, Yi-Yang Zhang, Yuan-Chen Dong,* Fen Wu, Chao Wang, Shuo Wang, Yun Xu, Dong-Sheng Liu.* The Investigation of the Stability of DNA-b-PPO Vesicles Formed through Frame Guided Assembly. Sci. China Chem. 2018, 61 (12), 1568-1571.
77. Yiyang Zhang, Dandan Bao, Shuo Wang, Yuanchen Dong, Fen Wu, Haitao Li,* Dongsheng Liu.* A Modularly Designable Vesicle for Sequentially Multiple Loading. Small 2018, 14 (8), 1703259.
78. Dianming Wang, Guoliang Zhang, Yiyang Zhang, Ling Xin, Yuanchen Dong, Yang Liu, Dongsheng Liu*. An Addressable 2D Heterogeneous Nanoreactor to Study the Enzyme-Catalyzed Reaction at the Interface. Small 2017, 13 (43), 1700594.
79. Humayun Sharif,# Yang Li#, Yuanchen Dong, Liyi Dong, Wei Li Wang, Youdong Mao, Hao Wu.* Cryo-EM Structure of the DNA-PK Holoenzyme. Proc. Natl. Acad. Sci. USA 2017, 114 (28), 7367-7372.
80. Ying Lu,# Jiayi Wu,# Yuanchen Dong, Shuobing Chen, Shuangwu Sun, Yong-Bei Ma, Qi Ouyang, Daniel Finley, Marc W. Kirschner,* Youdong Mao.* Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle. Mol. Cell 2017, 67 (2), 322-333.
81. Yuanchen Dong, Yuhe Renee Yang, Yiyang Zhang, Dianming Wang, Xixi Wei, Saswata Banerjee, Yan Liu, Zhongqiang Yang, Hao Yan,* Dongsheng Liu.* Cuboid Vesicles Formed by Frame-Guided Assembly on DNA Origami Scaffolds. Angew. Chem. Int. Ed. 2017, 56 (6), 1586-1589.
82. Jingsheng Zhou, Yuanchen Dong, Yiyang Zhang, Dongsheng Liu, Zhongqiang Yang.* The Assembly of DNA Amphiphiles at Liquid Crystal-Aqueous Interface. Nanomaterials 2016, 6 (12), 229.
83. Chao Zhou,# Yiyang Zhang,# Yuanchen Dong, Fen Wu, Dianming Wang, Ling Xin, Dongsheng Liu*. Precisely Controlled 2D Free-Floating Nanosheets of Amphiphilic Molecules through Frame-Guided Assembly. Adv. Mater. 2016, 28 (44), 9819-9823.
84. Dianming Wang, Yiyang Zhang, Miao Wang, Yuanchen Dong, Chao Zhou, Mark Antonin Isbell, Zhongqiang Yang, Huajie Liu, Dongsheng Liu.* A Switchable DNA Origami Nanochannel for Regulating Molecular Transport at the Nanometer Scale. Nanoscale 2016, 8 (7), 3944-3948.
85. Chao Zhou, Dianming Wang, Yuanchen Dong, Ling Xin, Yawei Sun, Zhongqiang Yang, Dongsheng Liu*. Preparation and Self-folding of Amphiphilic DNA Origami. Small 2015, 11 (9-10), 1161-1164.
86. Dianming Wang,# Ziran Da,# Bohan Zhang, Mark Antonin Isbell, Yuanchen Dong, Xu Zhou, Huajie Liu, Jerry Yong Yew Heng,* Zhongqiang Yang.* Stability Study of Tubular DNA Origami in the Presence of Protein Crystallisation Buffer. Rsc Advances 2015, 5 (72), 58734-58737.
87. Yuanchen Dong, Zhongqiang Yang, Dongsheng Liu*. Using Small Molecules to Prepare Vesicles with Designable Shapes and Sizes via Frame-Guided Assembly Strategy. Small 2015, 11 (31), 3768-3771.
88. Yuanchen Dong, Dongsheng Liu*. Frame-Guided Assembly of Amphiphiles. Chem. Eur. J. 2015, 21 (50), 18018-18023.
89. Tao Zhou, Yijie Wang, Yuanchen Dong, Chun Chen, Dongsheng Liu, Zhongqiang Yang.* Tetrahedron DNA Dendrimers and Their Encapsulation of Gold Nanoparticles. Bioorg. Med. Chem. 2014, 22 (16), 4391-4394.
90. Zhiyong Zhao, Chun Chen, Yuanchen Dong, Zhongqiang Yang, Qing-Hua Fan*, Dongsheng Liu*. Thermally Triggered Frame-Guided Assembly. Angew. Chem. Int. Ed. 2014, 53 (49), 13468-13470.
91. Yuanchen Dong, Zhongqiang Yang, Dongsheng Liu*. DNA Nanotechnology Based on i-Motif Structures. Acc. Chem. Res. 2014, 47 (6), 1853-1860.
92. Yuanchen Dong, Yawei Sun, Liying Wang, Dianming Wang, Tao Zhou, Zhongqiang Yang, Zhong Chen, Qiangbin Wang, Qinghua Fan, Dongsheng Liu*. Frame-Guided Assembly of Vesicles with Programmed Geometry and Dimensions. Angew. Chem. Int. Ed. 2014, 53 (10), 2607-2610.
93. Yuanchen Dong, Dongsheng Liu, Zhongqiang Yang*. A Brief Review of Methods for Terminal Functionalization of DNA. Methods 2014, 67 (2), 116-122.
94. Yuanchen Dong, Zhongqiang Yang*. Beyond Displays: The Recent Progress of Liquid Crystals for Bio/Chemical Detections. Chinese Sci. Bull. 2013, 58 (21), 2557-2562.
95. Tao Zhang, Yuanchen Dong, Yawei Sun, Ping Chen, Yang Yang, Chao Zhou, Lijin Xu,* Zhongqiang Yang,* Dongsheng Liu.* DNA Bimodified Gold Nanoparticles. Langmuir 2012, 28 (4), 1966-1970.
96. Tao Zhang, Ping Chen, Yawei Sun, Yongzheng Xing, Yang Yang, Yuanchen Dong, Lijin Xu, Zhongqiang Yang,* Dongsheng Liu.* A New Strategy Improves Assembly Efficiency of DNA Mono-Modified Gold Nanoparticles. Chem. Commun. 2011, 47 (20), 5774-5776.
Selected Invited Talks:
1. ChinaNANO 2019, 2019, Beijing, China
2. International Soft Matter Symposium 2019 and 8th China Soft Matter Day, 2019, Hanzhou, China
3. Youth Symposium on Nano-Science, 2019, Beijing, China.
