教育背景:
2010,香港大学,生物技术,博士
2006,中山大学,生化与分子生物,硕士
2003,中山大学,生物,学士
工作经历:
2015.08-至今,北京大学,研究员
2012.10-2015.07,美国马里兰大学环境科学中心,助理研究员
2011.05-2012.09,美国亚利桑那州立大学,博士后
2010.08-2011.04,香港大学,研究助理
研究兴趣:
油脂代谢,类胡萝卜素生物发生,藻类系统生物学以及合成生物学,藻类资源的开发利用
所获荣誉:
“博雅”青年学者(2017)
科研项目:
国家自然科学基金面上项目:微藻甘油三酯代谢的表观遗传调控机制研究 (31770048),2018-2021,65万,主持人
国家自然科学基金面上项目:微拟球藻Nannochloropsis光合生产二十碳五烯酸的调控机制研究(31571807),2016-2019,主持人,65万
美国TEDCO:Ultra-high density Haematococcus pluvialis culture strategy for astaxanthin production in a large scale bioreactor,2014-2015,4万美元,共同主持人
新加坡-北大低碳中心NRF:Development of Land-free Photobioreactor Systems for Bio-fixation of Carbon Dioxide by Microalgae for Biofuels and Bioproducts,2012-2016,360万新元,共同主持人
学术兼职:
美国遗传协会,会员
微藻生物质协会,会员
Frontiers in Marine Science,特刊编辑
期刊论文:(近5年代表性论文;#共同第一作者,*通讯作者)
Sun Z, Wei H, Zhou Z-g, Ashokkumar M, Liu J* (2018) Screening of Isochrysis Strains and Utilization of a Two-Stage Outdoor Cultivation Strategy for Algal Biomass and Lipid Production. Applied Biochemistry and Biotechnology, in press
Chen J, Leng L, Ye C, Lu Q, Addy M, Wang J, Liu J, Chen P, Ruan R, Zhou W (2018) A comparative study between fungal pellet- and spore-assisted microalgae harvesting methods for algae bioflocculation. Bioresource Technology, in press
Xin Y#, Lu Y#, Lee Y#, Wei L, Jia J, Wang Q, Wang D, Bai F, Hu H, Hu Q, Liu J*, Li Y*, Xu J* (2017) Producing designer oils in industrial microalgae by rational modulation of co-evolving type-2 diacylglycerol acyltransferases. Mol Plant, 10: 1523-1539
Sun Z, Chen Y, Mao X, Liu J* (2017) Physiological and biochemical changes reveal differential patterns of docosahexaenoic acid partitioning in two marine algal strains of Isochrysis. Mar Drugs, 15: 357
Wei HH, Shi Y, Ma XN, Pan Y, Hu HH, Li YT, Luo M, Gerken H, Liu J* (2017) A type I diacylglycerol acyltransferase modulates triacylglycerol biosynthesis and fatty acid composition in the oleaginous microalga Nannochloropsis oceanica. Biotechnology for Biofules, 10: 174
Yang B, Liu J*, Ma X, Guo B, Liu B, Wu T, Jiang Y, Chen F* (2017) Genetic engineering of the Calvin cycle toward enhanced photosynthetic CO2 fixation in microalgae. Biotechnology for Biofules, 10: 229 (Featured article)
Ma X, Liu B, Yang B, Guo B, Liu J*, Chen F* (2017) Physiochemical and gene expression analyses reveal differential responses of the marine oleaginous alga Nannochloropsis salina under different lipid-induction conditions. Journal of Applied Phycology, in press, https://link.springer.com/article/10.1007/s10811-017-1318-9
Ma X, Yao L, Yang B, Lee Y, Chen F*, Liu J* (2017) RNAi-mediated silencing of a pyruvate dehydrogenase kinase enhances triacylglycerol biosynthesis in the oleaginous marine alga Nannochloropsis salina. Scientific Reports, 7: 11485
Zhou WG*, Wang JH, Chen P, Ji C, Kang Q, Lu B, Li K, Liu J*, Ruan R (2017) Bio-mitigation of carbon dioxide using microalgal systems: advances and Perspectives. Renewable Sustainable Energy Reviews. 76: 1163-1175
Liu J*, Lee Y, Mao X, Li Y* (2017) A simple and reproducible non-radiolabeled in vitro assay for recombinant acyltransferases involved in triacylglycerol biosynthesis. J Appl Phycol, 29: 323-333
Liu J, Han D, Yoon K, Hu Q, Li Y (2016) Characterization of diacylglycerol acyltransferases in Chlamydomonas reinhardtii: Substrate specificity and their role in triacylglycerol biosynthesis. Plant J, 86: 3-19 (封面文章)
Liu J*, Mao X, Zhou W, Guarnieri M (2016) Simultaneous production of triacylglyerol and high-value carotenoids by the astaxanthin-producing oleaginous green microalga Chlorella zofingiensis. Bioresour Technol, 214: 319-327
Yang B, Liu J*, Jiang Y, Chen F* (2016) Chlorella species as hosts for genetic engineering and expression of recombinant proteins: Progress, challenge and perspective. Biotechnol J, 11:1244-1261 (封面文章)
Zhang Z, Sun D, Mao X, Liu J*, Chen F* (2016) The crosstalk between astaxanthin, fatty acids and reactive oxygen species in heterotrophic Chlorella zofingiensis. Algal Res, 19: 178-183
Guo B, Liu B, Yang B, Sun P, Lu X, Liu J*, Chen F* (2016) Screening of diatom strains and characterization of Cyclotella cryptica as a potential fucoxanthin producer. Mar Drugs, 14, 125
Ma X, Chen T, Yang B, Liu J*, Chen F* (2016) Lipid Production from Nannochloropsis. Mar Drugs 14: 61
Ma X, Liu J*, Liu B, Chen T, Jiang Y, Chen F* (2016) Physiological and biochemical changes reveal stress-associated photosynthetic carbon partitioning into triacylglycerol in the oleaginous marine alga Nannochloropsis oculata. Algal Res 16:28-35
Sun Z, Zhou Z-g, Gerken H, Chen F, Liu J* (2015). Screening and characterization of oleaginous Chlorella strains and exploration of photoautotrophic Chlorella protothecoides for oil production. Bioresour Technol 184: 53-62
Chen T#, Liu J#, Guo B, Ma X, Sun P, Liu B, Chen F (2015) Light attenuates lipid accumulation while enhancing cell proliferation and starch synthesis in the glucose-fed oleaginous microalga Chlorella zofingiensis. Sci Rep 5: 14936
Yang B, Liu J, Liu B, Sun P, Ma X, Chen F (2015) Development of a stable genetic system for Chlorella vulgaris—a promising green alga for CO2 biomitigation. Algal Res 12: 134-141
Liu B, Liu J, Sun P, Ma X, Jiang Y, Chen F (2015) Sesamol enhances cell growth and docosahexaenoic acid production in the microalga Crypthecodinium cohnii. J Agric Food Chem 63: 5640-5645
Liu B, Liu J, Chen T, Yang B, Jiang Y, Wei D, Chen F (2015). Rapid characterization of fatty acids in oleaginous microalgae by near-infrared spectroscopy for biodiesel production. Int J Mol Sci 16: 7045-7056
Liu J*, Sun Z, Gerken H, Huang J, Jiang Y, Chen F* (2014). Genetic engineering of the green alga Chlorella zofingiensis: a modified norflurazon-resistant phytoene desaturase gene as a dominant selectable marker. Appl Microbiol Biotechnol 98: 5069-5079
Liu J*, Sun Z, Gerken H, Liu Z, Jiang Y, Chen F* (2014). Chlorella zofingiensis as an Alternative Microalgal Producer of Astaxanthin: Biology and Industrial Potential. Mar Drugs 12: 3487-3515
Liu J*, Gerken H, Li Y* (2014). Single-tube colony PCR for DNA amplification and transformant screening of oleaginous microalgae. J Appl Phycol 26: 1719-1726
Wang Y, Liu J, Gerken H, Zhang C, Hu Q, Li Y (2014). Highly-efficient enzymatic conversion of crude algal oils into biodiesel. Bioresour Technol 172: 143-149
主编书籍
Liu J, Sun Z, Gerken H (2016) Recent advances in microalgal biotechnology. Omics Group. ISBN: 978-1-63278-066-9
专著章节
Liu J (2018) Batch cultivation for astaxanthin analysis using the green microalga Chlorella zofingiensis under multitrophic growth conditions. In: Carlos Barreiro and Jose-Luis Barredo (Eds). Microbial Carotenoids: Methods and Protocols. Springer Berlin Heidelberg, in press
Sun Z#, Liu J#, Zhou Z (2016) Algae for biofuels: An emerging feedstock. In: Rafael Luque, Carol Sze Ki Lin, Karen Wilson and James Clark (Eds). Handbook of Biofuels Production. 2nd. Woodhead Publishing, pp 673-698
Liu J, Chen F (2014). Biology and Industrial Applications of Chlorella: Advances and Prospects. in: Advances in Biochemical Engineering/Biotechnology. Springer Berlin Heidelberg, pp. 1-35. DOI: 10.1007/10_2014_286
Sun Z, Liu J* (2014) Microalgal Biofuels: Oil Biosynthesis, Biotechnology and Applications. In: Govil JN (Ed). Recent Developments in Biotechnology Vol. 3: Microbial Biotechnology. Studium Press LLC.
Liu J, Sun Z, Chen F (2013). Heterotrophic production of algal oils. In: Pandey A, Lee DJ, Chisti Y and Soccol CR (Eds), Algal Biofuels. Elsevier. Pp111-142
Liu J, Hu Q (2013) Chlorella – Industrial Production of Biomass and Chemicals. In: Richmond A and Hu Q (Eds), Handbook of Microalgal Cultures. 2nd Edition. Wiley Blackwell. pp. 327-338.